Results 61 to 70 of about 3,727,363 (257)

Longer Lives?: Understanding the Human Life Extension Possibilities [PDF]

open access: yes, 2017
Over the last few years, ethical and social issues related to life extension have gathered much attention among biologists, medical doctors and philosophers.
Garcia-Barranquero, Pablo
core  

Oral characteristics of Trisomy 8 and monosomy 18: a case report [PDF]

open access: yes, 2011
Several reports described various mosaic chromosomal syndromes characterized by alterations originated by either an excess or deficit in the number of chromosomes.
Campus, Guglielmo Giuseppe   +3 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Hands-on Clinical Clerkship at the Department of General Medicine in a University Hospital Improves Medical Students’ Self-Evaluation of Skills of Performing Physical Examinations and Informed Consent: A Questionnaire-Based Prospective Study

open access: yesInternational Journal of General Medicine, 2022
Yoshinori Tokushima,1,2 Masaki Tago,1,2 Midori Tokushima,1,3 Shun Yamashita,1 Yuka Hirakawa,1 Hidetoshi Aihara,1 Naoko E Katsuki,1 Motoshi Fujiwara,1 Shu-ichi Yamashita1 1Department of General Medicine, Saga University Hospital, Saga, Japan; 2Community ...
Tokushima Y   +8 more
doaj  

Rural Doctor Conversation [PDF]

open access: yes, 2010
South Asia in general, and India specifically, are regions with immense diversity in culture and language. Because of this conversations about medicine between doctors and patients takes different forms from one region to another. This is especially true
Joshi, Himanshu   +3 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Program development and initial experiences with the online class “Erste Hilfe Kasten – Allgemeinmedizin”

open access: yesGMS Journal for Medical Education
Objective: This project aims to provide doctors in postgraduate training (ÄiW) in general medicine with business knowledge of practice management through a modular training program within an e-learning environment, thereby reducing important barriers to ...
Seiler, Sabine   +3 more
doaj   +1 more source

short @nd sweet news : Nr. 9 [PDF]

open access: yes, 2007
* Change the Date: 1st Frankfurt General Practice Day * Summer Symposium of the Praxissiegel Foundation on July 6, 2007 * Revamp of the course "Introduction to Clinical Medicine" * Summer celebration for practice participants in the ...

core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Diagnosis and Treatment Protocol for COVID-19 Patients (Tentative 9th Version)

open access: yes​​​​​​​​Infectious Diseases & Immunity, 2022
The General Office of National Health Commission & the General Office of National Administration of Traditional Chinese Medicine   +1 more
doaj   +1 more source

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