Results 61 to 70 of about 14,404,861 (385)

Patient characteristics, resource use and outcomes associated with general internal medicine hospital care: the General Medicine Inpatient Initiative (GEMINI) retrospective cohort study.

CMAJ Open, 2017
BACKGROUND The precise scope of hospital care delivered under general internal medicine services remains poorly quantified. The purpose of this study was to describe the demographic characteristics, medical conditions, health outcomes and resource use of
A. Verma, Yishan Guo, J. Kwan, L. Lapointe-Shaw, S. Rawal, Terence Tang, A. Weinerman, P. Cram, I. Dhalla, Stephen W. Hwang, A. Laupacis, M. Mamdani, S. Shadowitz, Ross E. G. Upshur, R. Reid, F. Razak   +15 more
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

The Use of Telemetry Monitoring Among General Medicine Patients [PDF]

, 2017
Objective: To determine why and when general medicine non-ICU patients are upgraded from a non-telemetry level of care to telemetry monitoring at Thomas Jefferson University Hospital (TJUH).
Chen, MD, Debbie, Diemer, MD, Gretchen A.   +1 more
core   +1 more source

Swedish Medical LLM Benchmark: development and evaluation of a framework for assessing large language models in the Swedish medical domain

Frontiers in Artificial Intelligence
IntroductionWe present the Swedish Medical LLM Benchmark (SMLB), an evaluation framework for assessing large language models (LLMs) in the Swedish medical domain.MethodThe SMLB addresses the lack of language-specific, clinically relevant benchmarks by ...
Birger Moëll, Fabian Farestam, Jonas Beskow   +2 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

New Horizons in Psychiatry [PDF]

, 1971
Psychiatrists have long held that there should be more psychiatry in general medicine, and the nonpsychiatric physicians have said that there should be much more medicine in psychiatry.
Mathis, James L.
core   +1 more source

Factors associated with the choice of general medicine as a career among Japanese medical students

Medical Education Online, 2016
Background In Japan, there is a shortage of young physicians in various specialties; the present situation of general medicine or family medicine (GM/FM) in particular is risky.
R. Kawamoto, D. Ninomiya, Y. Kasai, T. Kusunoki, N. Ohtsuka, T. Kumagi, M. Abe   +6 more
semanticscholar   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

"It isn't just consultants that need a BSc": student experiences of an Intercalated BSc [PDF]

, 2005
More medical schools are moving towards a compulsory intercalated BSc. These courses have not traditionally been aimed at those students interested in general practice and have tended to have limited clinical relevance.
Jones, M., Lloyd, M., Singh, S.
core  

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source