Results 41 to 50 of about 777,287 (298)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The general meeting of participants of the limited company: theory and practice.
Теорія і практика правознавства, 2016 The legal regulation of the general meeting of participants as the supreme management body in limited companies is analyzed. Such actual problems as the procedure of convocation of the general meeting, their authority, methods of accepting decision by ...
Я. Л. Чернобук
doaj +1 more source
Proceedings of the 33rd Annual General Meeting of the Society of Mining Professors (SOMP) [PDF]
, 2023 core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Теорія і практика правознавства, 2016 Problem setting. In a modern period often enough declare requirements about confession invalid decisions of the general meeting. The imperfection of the legislative adjusting invalid decisions of the general meeting stipulated both in a doctrine and in ...
В. І. Крат
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
XXXVII General Meeting of EuroGeoSurveys (October 21–24, 2014, Bern, Switzerland)
Мінеральні ресурси України, 2014 The paper provides short description of the XXXVII General Meeting of EuroGeoSurveys, Association of Geological Surveys of Europe, held on October 21–24, 2014, in Bern, Switzerland.
B. I. Maliuk, S. I. Prymushko
doaj
Why adolescents peer group are not alike: the role of group functions.
, 2005 Social Identity Theory provides an important frame of reference to understand the processes linking adolescents to their peer groups, in that group membership provides an important contribution to their personal and collective self esteem which in turn ...
RUBINI M +3 more
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source