Results 41 to 50 of about 116,475 (314)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Association between weekday of surgery and length of hospital stay among patients undergoing primary total knee arthroplasty in Singapore: a secondary analysis based on a retrospective cohort study

Journal of Orthopaedic Surgery and Research
Background Total knee arthroplasty (TKA) demand is increasing globally, necessitating the optimization of hospital length of stay (LOS) to increase efficiency.
Yinping Liu, Guosong Xu, Zhensen He, Qun Chen   +3 more
doaj   +1 more source

Generalized least squares estimates for mixture of nonlinear regressions

Bulletin of Taras Shevchenko National University of Kyiv. Series: Physics and Mathematics, 2018
We consider data in which each observed subject belongs to one of different subpopulations (components). The true number of component which a subject belongs to is unknown, but the researcher knows the probabilities that a subject belongs to a given component (concentration of the component in the mixture).
openaire   +2 more sources

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source

Estimating test-day milk yields by modeling proportional daily yields: Going beyond linearity

Journal of Dairy Science, 2023
: In the United States, lactation milk yields are not measured directly but are calculated from the test-day milk yields. Still, test-day milk yields are estimated from partial yields obtained from single milkings.
Xiao-Lin Wu, George R. Wiggans, H. Duane Norman, Heather A. Enzenauer, Asha M. Miles, Curtis P. Van Tassell, Ransom L. Baldwin, VI, Javier Burchard, João Dürr   +8 more
doaj   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Fully complex-valued radial basis function networks: orthogonal least squares regression and classification [PDF]

, 2008
We consider a fully complex-valued radial basis function (RBF) network for regression and classification applications. For regression problems, the locally regularised orthogonal least squares (LROLS) algorithm aided with the D-optimality experimental ...
Harris, C. J., Hong, Xia, Chen, Sheng, Hong, X., Harris, Chris J., Hanzo, Lajos, Hanzo, L., Chen, S.   +7 more
core   +1 more source

Detection of nonlinearity, discontinuity and interactions in generalized regression models

Statistical Modelling
In generalized regression models, the effect of continuous covariates is commonly assumed to be linear. This assumption, however, may be too restrictive in applications and may lead to biased effect estimates and decreased predictive ability. While a multitude of alternatives for the flexible modelling of continuous covariates have been proposed ...
Spuck, Nikolai, Schmid, Matthias, Berger, Moritz   +2 more
openaire   +2 more sources

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

Advanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares, Nadège Bouchonneau, Christian Jochum, Donald Radford   +3 more
wiley   +1 more source