Results 71 to 80 of about 1,270,255 (358)
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Partnership law in the twenty-first century [PDF]
Discusses reforms to partnership law that have been proposed by the Law Commission and the Scottish Law Commission in their 'Partnership Law: a Joint Consultation Paper', and considers whether the reforms are necessary or not and what effect they are ...
Deards, E
core
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
ON THE SPECIFICS OF PUBLIC-PRIVATE PARTNERSHIP IN RUSSIAN AND FOREIGN PRACTICE
The article examines the importance of public-private partnership at the current stage of development of the Russian economy. The basic features of the public-private partnership system in a number of leading countries of the world are studied.
R. Ustaev, V. Parakhina, Z. Shalashaa
doaj
SPECIFICITIES OF CORPORATE GOVERNANCE IN SMALL BUSINESS ENTERPRISES OF UZBEKISTAN
It is commonly known that the corporate governance is a way of management which is intrinsic to the large corporate structures. Today, in Uzbekistan such corporate structures mainly function in the form of joint-stock companies, limited liability ...
Zufar Ashurov
doaj +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Background: The World Health Organization HIV guidelines recommend either infant zidovudine (ZDV) or nevirapine (NVP) prophylaxis for the prevention of intrapartum motherto-child HIV transmission (MTCT) among formula-fed infants.
Kathleen M. Powis +15 more
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Partnership with suppliers is becoming a critical activity in retail industry to strengthen their competitive position. However, evidence suggested that partnership efforts do not reach their potential due to the effect of external factors.
Agus W. Soehadi
doaj +1 more source
Toward a Real Simple Taxonomy: Bridging Learners and Content to Create New Value at LearnPhilanthropy [PDF]
LearnPhilanthropy is bringing together the wealth of research, resources and ideas on good practice from sources across the sector: Imagine a farmer's market providing fresh products from a variety of producers, all in one place, as well as a gathering ...
Dara Major
core

