Results 31 to 40 of about 176,292 (215)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Exploring Freshmen’s Insight on Physics Measurement Uncertainty: Voices from the General Physics Course

Jurnal Pendidikan Sains Universitas Muhammadiyah Semarang
Since secondary school, students have always learned measurement accuracy. Understanding measurement uncertainty is crucial, as is acquiring, handling, and analyzing measurement data.
Muhamad Arif Mahdiannur
doaj   +1 more source

Calculus in physics classes at UFRGS: an exploratory study [PDF]

Investigações em Ensino de Ciências, 2011
This study is part f a larger one whose general objective is to investigate and to develop a new strategy for teaching Differential and Integral Calculus I, specifically for physics majors, through a possible integration with the teaching of General and ...
Maria Cecilia Pereira Santarosa, Marco Antonio Moreira   +1 more
doaj  

On the Mathematics of Coframe Formalism and Einstein–Cartan Theory—A Brief Review

Universe, 2019
This article is a review of what could be considered the basic mathematics of Einstein−Cartan theory. We discuss the formalism of principal bundles, principal connections, curvature forms, gauge fields, torsion form, and Bianchi identities, and ...
Manuel Tecchiolli
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Dark Matter physics in general NMSSM

Journal of High Energy Physics
In the General Next-to-Minimal Supersymmetric Standard Model (GNMSSM), singlet particles may form a secluded sector of dark matter (DM), in which Singlino-like DM could achieve the observed relic abundance through various channels such as χ ~ 1 0 χ ~ 1 0
Lei Meng, Junjie Cao, Fei Li, Shenshen Yang   +3 more
doaj   +1 more source

Laws of general solutions of mathematical physics equations

Partial Differential Equations in Applied Mathematics
In this paper, the general solutions of five important mathematical physics equations are obtained for the first time, using the Z transformations that we have previously proposed.
Hong Lai Zhu
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source