Results 131 to 140 of about 3,461,205 (298)

Nocturnal Leg Cramps and Lumbar Spinal Stenosis: A Cross-Sectional Study in the Community

open access: yesInternational Journal of General Medicine, 2022
Junichi Handa, Koji Otani, Takuya Nikaido, Shin-ichi Kikuchi ,† Shin-ichi Konno Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan†Shin-ichi Kikuchi passed away on February 22th, 2022Correspondence ...
Handa J   +4 more
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The need for psychiatric treatment in the general population: the Camberwell Needs for Care Survey

open access: yes, 1997
Background, This paper presents the first results of a two-stage psychiatric population survey, which uses a new method of directly evaluating needs for specific psychiatric treatment and the extent to which they have been met.Method, The sample was ...
Bebbington, PE   +5 more
core   +1 more source

A Generalized Approach to Population Synthesis

open access: yes, 2017
Agent-based microsimulation model systems for transportation planning operate at the level of individual agents, and allow more detailed simulation and analysis than traditional four-step models. At the core of any agent-based model is the synthetic population, a disaggregate representation of the agents in the study area. While population synthesis of
openaire   +2 more sources

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Can general practitioners influence the nation's health through a population approach to the provision of lifestyle advice?

open access: yes, 2000
BACKGROUND: Lifestyle advice from general practitioners (GPs) has been shown to have a positive effect on population health. In practice, GPs provide lifestyle advice to a minority of their patients only, those who are high risk or already have symptoms.
Keen, Steven   +2 more
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

IPUMSI - Brazil 1980 - enumerator instructions - english

open access: yes, 2004
Translation of original enumeration instructions into English. Only sections required for the IPUMS International data system were translated.Funding provided by the National Institute of Child Health and Human Development (HD044154).Minnesota Population
Minnesota Population Center
core  

Patterns of health service utilisation among the Australian population with cancer compared to the general population

open access: yes, 2018
Aim: To evaluate patterns of health service utilisation among the Australian population with cancer compared with the general population. Methods: Data for all the respondents aged 25 years and above from two successive Australian National Health ...
Ng, Huah Shin   +4 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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