Results 41 to 50 of about 2,657,945 (266)

Development of a performance measurement system for general practitioners’ office in China’s primary healthcare

open access: yesBMC Health Services Research, 2022
Background General practitioners are the main providers of primary care services. To better strengthen the important role of general practitioners in primary healthcare services, China is promoting the general practitioners’ office system.
Wenjie Ruan   +6 more
doaj   +1 more source

Practical Calculation Scheme for Generalized Seniority [PDF]

open access: yes, 2014
We propose a scheme or procedure for doing practical calculations with generalized seniority. It reduces the total computing time by calculating and storing in advance a set of intermediate quantities, taking advantage of the memory capability of modern computers. The requirements and performance of the algorithm are analyzed in detail.
arxiv   +1 more source

Evaluating the origin and spread of spotted lanternfly (Lycorma delicatula) in Japan

open access: yesPopulation Ecology, EarlyView.
The invasive spotted lanternfly (Lycorma delicatula) is native to China and is a serious economic pest in the Republic of Korea and the United States, though it is not considered a pest in Japan. We established a distribution map of L. delicatula in Japan through a comprehensive review of published literature and citizen science reports and analyzed ...
Matthew T. Kamiyama   +5 more
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Professional roles of general practitioners, community pharmacists and specialist providers in collaborative medication deprescribing - a qualitative study

open access: yesBMC Family Practice, 2020
Background Collaborative care approaches between general practitioners (GPs) and pharmacists have received international recognition for medication optimization and deprescribing efforts.
Navina Gerlach   +6 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

Analysis of Software Engineering Practices in General Software and Machine Learning Startups [PDF]

open access: yesarXiv, 2023
Context: On top of the inherent challenges startup software companies face applying proper software engineering practices, the non-deterministic nature of machine learning techniques makes it even more difficult for machine learning (ML) startups.
arxiv  

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

Colleague appraisal of Australian general practitioners in training: an analysis of multisource feedback data

open access: yesBMC Medical Education, 2022
Background Multisource feedback is an evidence-based and validated tool used to provide clinicians, including those in training, feedback on their professional and interpersonal skills.
Caitlin Vayro   +7 more
doaj   +1 more source

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