Results 111 to 120 of about 14,384,400 (302)

Application of the privacy principles to general practice

open access: yes, 2001
Copyright © 2001 Royal Australian College of General Practitioners Copyright to Australian Family Physician. Reproduced with permission. Permission to reproduce must be sought from the publisher, The Royal Australian College of General Practitioners ...
Mulligan, E.   +2 more
core  

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

PRINCIPLES OF GENERAL PHYSIOLOGY

open access: yesThe Journal of Nervous and Mental Disease, 1922
Fourth edition ; XXVIII, 882 pages : illustrations ; 25 cm ; Bibliography and indexes ; Fourth edition ; XXVIII, 882 strony : ilustracje ; 25 cm ; Bibliografia ...
openaire   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

On the General Taxation Principles [PDF]

open access: yes, 2019
The paper consists of two parts. The first presents a catalogue of general taxation principles that have been formulated by prominent theoreticians over the last two hundred years, starting from A. Smith, through D. Ricardo, J.S. Mill, A.
Harasimowicz, Jerzy
core  

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta   +11 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

EVIDENCE-BASED MEDICINE – I. GENERAL PRINCIPLES

open access: yesZdravniški Vestnik, 2003
Background. Evidence-based medicine is a method that helps physicians find and critically evaluate evidences from the medical literature, and apply the evidences in clinical decision-making. In clinical practice the method supplements core medical skills,
Angela Čuk
doaj  

Charge Steering in Heterojunction Photocatalysis: General Principles, Design, Construction, and Challenges. [PDF]

open access: yesSmall Sci, 2023
Eshete M   +8 more
europepmc   +1 more source

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