Results 101 to 110 of about 11,515,194 (303)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The State of Science-and-Religion Scholarship At The Turn of the Century [PDF]
, 2012 In this keynote address to the 2000 Science and Religion Colloquium, the author not only describes and assesses the state of religion-and-science scholarship at the turn of the century hut also proposes a new approach for guiding it into the new century.
Wildman, Wesley J.
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Teaching trust in science: a critical new focus for science education
Frontiers in CommunicationThe recent pandemic has revealed the importance of understanding how scientific knowledge is produced, if citizens are to make decisions that protect themselves, their communities, and their nations. Creating such an understanding presents a critical and
Karen Hopkin +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
, 2004 This is a web version of a brochure produced by the American Geological Institute to inform people about the importance of Earth science education in K-12 schooling. Educational levels: General public, High school, Intermediate elementary, Middle school,
Michael Smith
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hands-on Physical Science Course at Radford University [PDF]
, 1999 Most students in our introductory physical science course are elementary education majors. We are faced with several obstacles in teaching basic science to these students.
Tanaka, T.
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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A New ‘Idea of Nature’ for Chemical Education [PDF]
, 2013 This paper recommends that chemistry educators shift to a different ‘idea of nature’, an alternative ‘worldview.’ Much of contemporary science and technology deals in one way or another with dynamic coherences that display novel and important properties.
Earley, Joseph E.
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