Results 121 to 130 of about 85,942 (221)

A Complementarity‐Based Approach to De Novo Binder Design

Advanced Science, Volume 12, Issue 33, September 4, 2025.
A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko, Valeriia Hatskovska, Murray Coles, Narges Aghaallaei, Natalia Pashkovskaia, Natalia Borbarán‐Bravo, Matteo Pilz, Philip Bucher, Mareike Volz, Joana Pereira, Marcus D. Hartmann, Ghazaleh Tabatabai, Judith Feucht, Stefan Liebau, Patrick Müller, Andrei N. Lupas, Julia Skokowa, Mohammad ElGamacy   +17 more
wiley   +1 more source

Random Walks and Lorentz Processes. [PDF]

Entropy (Basel)
Szász D.
europepmc   +1 more source

An Approach to Locally Convex Topological Linear Spaces

, 1964
K. Iseki
semanticscholar   +1 more source

First‐order Sobolev spaces, self‐similar energies and energy measures on the Sierpiński carpet

Communications on Pure and Applied Mathematics, Volume 78, Issue 9, Page 1523-1608, September 2025.
Abstract For any p∈(1,∞)$p \in (1,\infty)$, we construct p$p$‐energies and the corresponding p$p$‐energy measures on the Sierpiński carpet. A salient feature of our Sobolev space is the self‐similarity of energy. An important motivation for the construction of self‐similar energy and energy measures is to determine whether or not the Ahlfors regular ...
Mathav Murugan, Ryosuke Shimizu
wiley   +1 more source

Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories. [PDF]

Elife
Rg R, Ascoli GA, Sutton NM, Dannenberg H.   +3 more
europepmc   +1 more source

The porous medium equation: Large deviations and gradient flow with degenerate and unbounded diffusion

Communications on Pure and Applied Mathematics, Volume 78, Issue 9, Page 1609-1655, September 2025.
Abstract The problem of deriving a gradient flow structure for the porous medium equation which is thermodynamic, in that it arises from the large deviations of some microscopic particle system is studied. To this end, a rescaled zero‐range process with jump rate g(k)=kα,α>1$g(k)=k^\alpha, \alpha >1$ is considered, and its hydrodynamic limit and ...
Benjamin Gess, Daniel Heydecker
wiley   +1 more source

NONLINEAR GLOBAL FRÉCHET REGRESSION FOR RANDOM OBJECTS VIA WEAK CONDITIONAL EXPECTATION. [PDF]

Ann Stat
Bhattacharjee S, Li B, Xue L.
europepmc   +1 more source

Homology and cohomology with compact supports forq-convex spaces

, 1991
G. Forni
semanticscholar   +1 more source

Uniqueness on average of large isoperimetric sets in noncompact manifolds with nonnegative Ricci curvature

Communications on Pure and Applied Mathematics, Volume 78, Issue 9, Page 1656-1702, September 2025.
Abstract Let (Mn,g)$(M^n,g)$ be a complete Riemannian manifold which is not isometric to Rn$\mathbb {R}^n$, has nonnegative Ricci curvature, Euclidean volume growth, and quadratic Riemann curvature decay. We prove that there exists a set G⊂(0,∞)$\mathcal {G}\subset (0,\infty)$ with density 1 at infinity such that for every V∈G$V\in \mathcal {G}$ there ...
Gioacchino Antonelli, Marco Pozzetta, Daniele Semola   +2 more
wiley   +1 more source

Dynamic Balance: A Thermodynamic Principle for the Emergence of the Golden Ratio in Open Non-Equilibrium Steady States. [PDF]

Entropy (Basel)
Ruiz A.
europepmc   +1 more source