The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
Magnetic Field-Driven Strategies for Biofilm Disruption: From Iron Oxide Nanoparticles to Adaptive Swarms of Magnetic Microrobots. [PDF]
Caf M +10 more
europepmc +1 more source
A portable, sensorized, and controlled dexterous thumb‐enhanced glove helps stroke survivors swipe phones, twist caps, and perform other tasks. It is based on a powerful continuously, segmented origami dual chamber actuator to achieve active thumb CMC and MCP joint assistance and passively extend the IP joint.
Disheng Xie +10 more
wiley +1 more source
Control of flow behavior in complex fluids using automatic differentiation. [PDF]
Alhashim MG, Hausknecht K, Brenner MP.
europepmc +1 more source
THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong +16 more
wiley +1 more source
Instability of Oldroyd-B Liquid Films with Odd Viscosity on Porous Inclined Substrates. [PDF]
Zhou Q, Liu Q, Zhang R, Ding Z.
europepmc +1 more source
From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics
Mechanical properties of the oocyte are increasingly recognized as critical determinants of meiotic success and developmental potential. How actomyosin remodeling controls oocyte mechanics, how these properties are altered in pathological conditions, and how they could serve as markers in reproductive medicine are examined.
Anastasia Shihabi +3 more
wiley +1 more source
A New Type of Hydraulic Clutch with Magnetorheological Fluid: Theory and Experiment. [PDF]
Musiałek K +7 more
europepmc +1 more source
Computational methods for inertial microfluidics: recent advances and future perspectives. [PDF]
Lauricella G +6 more
europepmc +1 more source

