Results 141 to 150 of about 2,927 (171)

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Measuring and valuing spillover effects in caregivers and families: A scoping review. [PDF]

PLoS One
Dang TTH, Tabinga A, Beilby H, Barker N, Johnson LR, Tuffaha H, Connelly LB, Maguire AM.   +7 more
europepmc   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Efficient data selection for time series forecasting using a lightweight linear proxy framework. [PDF]

Sci Rep
Ao X, Chen M.
europepmc   +1 more source

Further examining how animals weigh conflicting information about reward sources over time. [PDF]

Anim Cogn
Van Allsburg J, Shahan TA.
europepmc   +1 more source

On <i>p</i>-adic <i>L</i>-functions for symplectic representations of GL ( N ) over number fields. [PDF]

Res Math Sci
Williams C.
europepmc   +1 more source

Blockchain-enabled strategic optimization: A decision analytics framework for multinational enterprises' e-commerce entry model. [PDF]

PLoS One
Deng L, Hu X, Xiao Y.
europepmc   +1 more source

Continuous attractor dynamics in spatial navigation: from population geometry to flexible computation. [PDF]

Front Neurosci
Chen Y, Hua M, Sun X, Peng J.
europepmc   +1 more source

Postural health education in schools: teachers' perspectives on well-being, inequities, and institutional constraints. [PDF]

Int J Qual Stud Health Well-being
García-Luna MA, Cunha AC, Manchado C, Cortell-Tormo JM.   +3 more
europepmc   +1 more source