Results 131 to 140 of about 42,198 (272)

Posterior cruciate ligament management in medial pivot total knee arthroplasty: a systematic review and meta-analysis. [PDF]

J Orthop Surg Res
Migliorini F, Pilone M, Schäfer L, Vaishya R, Moretti G, Mendel T, Pipino G, Maffulli N.   +7 more
europepmc   +1 more source

Book Reviews [PDF]

, 1952

core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Exploring advancements in the management of penile cancer in the era of artificial intelligence and machine learning: a narrative review. [PDF]

Ann Med Surg (Lond)
Ali RN, Irfan S, Anwaar A, Anwar MS, Ul Haq I, Irfan M, Ghouri MS, Irfan W, Akilimali A.   +8 more
europepmc   +1 more source

Level I of evidence does not support manual lymphatic drainage for total knee arthroplasty: a meta-analysis. [PDF]

Sci Rep, 2023
Migliorini F, Schäfer L, Bertini FA, Memminger MK, Simeone F, Giorgino R, Maffulli N.   +6 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Long-term outcomes of arthroscopic management of femoroacetabular impingement syndrome: a systematic review. [PDF]

Arch Orthop Trauma Surg
Migliorini F, Vaishya R, Simeone F, Memminger MK, Betsch M, Pasurka M.   +5 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

"Tough Things You're Going to Have to Go Through": Dyadic Interview Study Including the Perspectives and Needs of Patients and Their Caregivers Post-Hematopoietic Cell Transplant. [PDF]

J Particip Med
Johnson A, Smeallie E, Roslin C, Rozwadowski M, Shereck E, Choi SW.   +5 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source