Results 161 to 170 of about 42,198 (272)

Intra-articular injections for shoulder arthritis in adults: a systematic review. [PDF]

Eur J Med Res
Migliorini F, Schäfer L, Masoni V, Rivera F, Pipino G, Maffulli N.   +5 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Management of coccygodynia: talking points from a systematic review of recent clinical trials. [PDF]

Ann Jt
Mazzoleni MG, Maffulli N, Bardazzi T, Memminger M, Bertini FA, Migliorini F.   +5 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Virulence evolution of a salmonid virus following a host jump. [PDF]

PLoS Pathog
Loeher MM, Kurath G, Kennedy DA, Salzer JE, Batts WN, Breyta RB, Wargo AR.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Delayed flowering phenology of red-flowering plants in response to hummingbird migration. [PDF]

Curr Biol
McKenzie PF, Berardi AE, Hopkins R.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Use of a mobile app and educational website to promote metabolic control in people with type 2 diabetes: study protocol for a multicenter clinical trial. [PDF]

Front Health Serv
Velázquez López L, Ortíz GO, Klünder MK, Gil JV, Del Aguila IP, Medina Gómez OS, de la Peña JE, “Entiendo mi diabetes” Investigators Group.   +7 more
europepmc   +1 more source

General science books [PDF]

General Science Quarterly, 1918
openaire   +1 more source