Results 241 to 250 of about 315,175 (297)

Imbalanced Fault Diagnosis of Electromechanical Systems Under Unseen Operating Conditions: A Heterogeneous Domain Generalization Framework Combining Digital Twin Knowledge and Data

Xuanyuan Su, Kaixin Jin, Yan Ma, Lu Chen, Laifa Tao   +4 more
openalex   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Critical considerations for the use of deep learning models in clinical oncology prediction. [PDF]

Front Oncol
Zhao D.
europepmc   +1 more source

GeoCrossBench: Cross-Band Generalization for Remote Sensing

Tamazyan, Hakob, Vanyan, Ani, Barseghyan, Alvard, Khosrovyan, Anna, Shelhamer, Evan, Khachatrian, Hrant   +5 more
openalex   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Benchmarking community drug response prediction models: datasets, models, tools, and metrics for cross-dataset generalization analysis. [PDF]

Brief Bioinform
Partin A, Vasanthakumari P, Narykov O, Wilke A, Koussa N, Jones SE, Zhu Y, Overbeek JC, Jain R, Fernando GD, Sanchez-Villalobos C, Garcia-Cardona C, Mohd-Yusof J, Chia N, Wozniak JM, Ghosh S, Pal R, Brettin TS, Weil MR, Stevens RL.   +19 more
europepmc   +1 more source

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

FEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo, Emma Piccoli, Luca Bombardi, Martina Aulitto, Salvatore Fusco   +4 more
wiley   +1 more source

Which Word Orders Facilitate Length Generalization in LMs? An Investigation with GCG-Based Artificial Languages

Association for Computational Linguistics 2025, Briscoe, Ted, El-Naggar, Nadine, El-Naggar, Nadine, Kuribayashi, Tatsuki   +4 more
openalex   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Molecular graph-based invariant representation learning with environmental inference and subgraph generation for out-of-distribution generalization. [PDF]

J Cheminform
Zhu H, Yuan S, Tang M, Zhou G, Hu Z, Liu Z, Li J, Wang J, Li C.   +8 more
europepmc   +1 more source