Results 191 to 200 of about 261,260 (312)

Associations Between Nicotine Metabolites and Serum Neurofilament Light Chain Levels in the General Population

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background Nicotine has been associated with cognitive functions such as memory and attention, with serum neurofilament light chain (sNfL) as a biomarker for neurological diseases such as Alzheimer's disease (AD) and multiple sclerosis (MS).
Qianqian Ji, Erhan Tang, Yueting Liao, Jialei Yang, Yunzhang Wang, Yiqiang Zhan   +5 more
wiley   +1 more source

Incidence and Risk Patterns of Anxiety and Depressive Disorders and Categorization of Generalized Anxiety Disorder [PDF]

, 2010
Katja Beesdo‐Baum, Daniel S. Pine, Roselind Lieb, Hans‐Ulrich Wïttchen   +3 more
openalex   +1 more source

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

Clinical Pharmacology in Drug Development, EarlyView.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan, Elizabeth Doolin, Dharam Paul, Julia Crossman, Michael Odontiadis, Philippe Danjou, Mark Smith, Spyros Papapetropoulos   +7 more
wiley   +1 more source

Intolerance of Uncertainty and Emotion Regulation in Generalized Anxiety Disorder: The Role of Reappraisal and Suppression. [PDF]

Behav Sci (Basel)
Sun L, Zou H, Li W, Li H, Pang J, Cui H, Li C.   +6 more
europepmc   +1 more source

Factor structure and construct validity of the Generalized Anxiety Disorder 7-item (GAD-7) among Portuguese college students [PDF]

, 2017
Ana Bártolo, Sara Monteiro›, Anabela Pereira   +2 more
openalex   +1 more source

The reliability, validity and factorial structure of the Swahili version of the 7-item generalized anxiety disorder scale (GAD-7) among adults living with HIV from Kilifi, Kenya [PDF]

, 2020
Moses K. Nyongesa, Paul Mwangi, Hans M. Koot, Pim Cuijpers, Charles R. Newton, Amina Abubakar   +5 more
openalex   +1 more source

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali, Stephan van Erp, Cornelis Kramers, Cornelis J. Tack, Bastiaan E. de Galan   +4 more
wiley   +1 more source

ZDHHC5 Mediates Immune Dysregulation Driving Generalized Anxiety Disorder Risk. [PDF]

Brain Behav
Sun F, Lu G, Li N, Dai K, Ren Z, Ma R, Feng Y, Zong S, Cheng B.   +8 more
europepmc   +1 more source

The Light and Shadow of Smartphone Applications for Eating Disorders: Commentary on Cruz et al. (2025)

International Journal of Eating Disorders, EarlyView.
ABSTRACT Smartphone applications (apps) represent promising tools to overcome common barriers to treatment in individuals within the Eating Disorders (EDs) spectrum, thanks to their constant availability and cost‐effectiveness. In this context, Cruz et al.
Silvia Cerea
wiley   +1 more source

Generalized Anxiety Disorder and Obesity: Overlapping Neuroendocrine, Metabolic, and Behavioral Pathways. [PDF]

Nutrients
Dymek A, Zielińska M, Englert-Bator A, Dereń K, Łuszczki E.   +4 more
europepmc   +1 more source