ABSTRACT Introduction In real‐world practice in Japan, standard treatment for metastatic hormone‐naïve prostate cancer (mHNPC) is androgen deprivation therapy (ADT), administered as monotherapy, combined androgen blockade (CAB), ADT plus androgen receptor pathway inhibitors (ARPIs), or ADT plus docetaxel.
Atsushi Mizokami +14 more
wiley +1 more source
Causal Inference for Hypertension Prediction With Wearable E lectrocardiogram and P hotoplethysmogram Signals: Feasibility Study. [PDF]
Gon G K, Chen Y, Song X, Fu Z, Ding X.
europepmc +1 more source
Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks +3 more
wiley +1 more source
Randomised Badger Culling Trial-no effects of widespread badger culling on tuberculosis in cattle: comment on Mills, Woodroffe and Donnelly (2024a, 2024b). [PDF]
Torgerson PR +5 more
europepmc +1 more source
The continuing significance of chiral agrochemicals
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Interpretable machine learning models for predicting cognitive impairment using NHANES neuropsychological tests: nutritional and sociodemographic associations. [PDF]
Song L, Li C, Xiang X, Lin P.
europepmc +1 more source
An objective Bayesian method for including parameter uncertainty in ensemble model output statistics
Conventional model output statistics and ensemble model output statistics methods for calibrating ensemble forecasts lead to severe underestimation of the probabilities of ensemble extremes (in blue). This is because they ignore statistical parameter uncertainty.
Stephen Jewson +4 more
wiley +1 more source
Improving statistical reporting in psychology. [PDF]
Schubert AL +3 more
europepmc +1 more source
ABSTRACT This work presents a non‐geometrical navigation approach based on a purely topological understanding of underground environments. By conceptualizing subterranean scenarios as a set of tunnels that intersect with each other, and taking a navigation approach based on topological instructions, we simplify the navigation problem to the sequential ...
Lorenzo Cano +2 more
wiley +1 more source
Machine learning-guided identification and simulation-based validation of potent JAK3 inhibitors for cancer therapy. [PDF]
Wei H, Wang Q.
europepmc +1 more source

