Results 21 to 30 of about 56,385 (212)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Game theory, maximum entropy, minimum discrepancy and robust Bayesian decision theory
, 2002 We describe and develop a close relationship between two problems that have customarily been regarded as distinct: that of maximizing entropy, and that of minimizing worst-case expected loss. Using a formulation grounded in the equilibrium theory of zero-
Dawid, A. Philip, Grunwald, Peter D.
core +5 more sources
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Fast DD-classification of functional data
, 2016 A fast nonparametric procedure for classifying functional data is introduced. It consists of a two-step transformation of the original data plus a classifier operating on a low-dimensional hypercube.
Mosler, Karl, Mozharovskyi, Pavlo
core +2 more sources
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Measuring questions: relevance and its relation to entropy
, 2004 The Boolean lattice of logical statements induces the free distributive lattice of questions. Inclusion on this lattice is based on whether one question answers another.
Knuth, Kevin H.
core +2 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Semi-supervised Learning Guided by the Generalized Bayes Rule Under Soft Revision
We provide a theoretical and computational investigation of the Gamma-Maximin method with soft revision, which was recently proposed as a robust criterion for pseudo-label selection (PLS) in semi-supervised learning. Opposed to traditional methods for PLS we use credal sets of priors ("generalized Bayes") to represent the epistemic modeling uncertainty.
Dietrich, Stefan +2 more
openaire +4 more sources
Dual‐Ligand Metal‐Organic Frameworks via In Situ Amidoxime Engineering for Selective Ion Separation
Advanced Functional Materials, EarlyView.Inspired by microbial ion‐trapping mechanisms, a mild and universal strategy is developed to construct highly porous amidoxime‐functionalized MOFs. DFT calculations and molecular force measurements reveal that the dual‐ligand amidoxime configuration significantly strengthens Ga(III) affinity.
Zhifang Lv +9 more
wiley +1 more source
The quantum Bayes rule and generalizations from the quantum maximum entropy method
Journal of Physics Communications, 2018 The recent article "Entropic Updating of Probability and Density Matrices" [1] derives and demonstrates the inferential origins of both the standard and quantum relative entropies in unison. Operationally, the standard and quantum relative entropies are shown to be designed for the purpose of inferentially updating probability distributions and density
openaire +2 more sources