Results 41 to 50 of about 1,514 (136)

Analysis of severe cutaneous adverse reactions (SCARs) in Taiwan drug-injury relief system: 18-year results

Journal of the Formosan Medical Association, 2022
Background/purpose: Taiwan Drug-Injury Relief System (TDRS) has been implemented since 1999. More than 60% of the approved applications were associated with severe cutaneous adverse reactions (SCARs). Studies assessing SCARs using real-world evidence are
Po-Wei Huang, Mu-Han Chiou, Mei-Yi Chien, Wen-Wen Chen, Chia-Yu Chu   +4 more
doaj   +1 more source

Oral Lichenoid Reactions Caused by Mesalazine for Treatment of Ulcerative Colitis: A Case Report and Review of the Literature. [PDF]

Case Rep Dent
Background Mesalazine, also known as 5‐aminosalicylic acid (5‐ASA), is commonly used to treat ulcerative colitis and Crohn′s disease. While various adverse effects of mesalazine have been reported, oral lichenoid reactions (OLRs) are rarely associated with its use.
Diamanti S, Solomou MM.
europepmc   +2 more sources

Naproxen-induced generalized bullous fixed drug eruption

Dermatology Online Journal, 2009
A fixed drug eruption (FDE) is a cutaneous reaction to an ingested drug that recurs at the same site each time the offending drug is taken. Clinical diagnosis may be difficult as patients often do not consider over-the-counter medications or supplements as part of their reported medication list.
Bandino, Justin P, Wohltmann, Wendi E, Bray, David W, Hoover, Aaron Z   +3 more
openaire   +4 more sources

Clinical Features and Drug Characteristics of Patients with Generalized Fixed Drug Eruption in the West of Iran (2005–2014)

Dermatology Research and Practice, 2015
Background. Generalized fixed drug eruption is a specific variant of fixed drug eruption with multifocal lesions. Diagnosis of this drug reaction is straightforward, but occasionally recognition of the causative drug is not possible. This study was aimed
Hossein Kavoussi, Mansour Rezaei, Katayoun Derakhshandeh, Alireza Moradi, Ali Ebrahimi, Harif Rashidian, Reza Kavoussi   +6 more
doaj   +1 more source

Acetaminophen-induced cellulitis-like fixed drug eruption

Indian Journal of Dermatology, 2011
Acetaminophen is a widely used analgesic drug. Its adverse reactions are rare but severe. An 89-year-old man developed an indurated edematous and erythematous plaque on his left arm 1 day after acetaminophen ingestion.
Neila Fathallah, Chaker Ben Salem, Raoudha Slim, Lobna Boussofara, Najet Ghariani, Kamel Bouraoui   +5 more
doaj   +1 more source

Fixed Drug Eruption in an Epileptic Patient Previously Receiving Treatment With Phenytoin for Seven Years

Journal of Investigative Medicine High Impact Case Reports, 2013
A 52-year-old African American female presented with severe left thigh pain of unknown etiology. She had a past medical history of generalized seizure disorder treated with phenytoin for 7 years without incident.
Keaton S. Smetana, Katie J. Suda PharmD, MS, Leslie A. Hamilton PharmD   +2 more
doaj   +1 more source

A case of generalized bullous fixed drug eruption mimicking Stevens-Johnson syndrome

Intisari Sains Medis
Introduction: Generalized bullous fixed drug eruption (GBFDE) is a rare variant of fixed drug eruption (FDE) and has a clinical picture of dark purplish erythematous patches accompanied by bullae that break easily, leaving large erosive lesions.
I. Halim, I. Praharsini, Luh Made Mas Rusyati, N. Karna, Harry Gunawan, Nadia Puspa Dewi   +5 more
semanticscholar   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Processionary Moth Exposure in Europe: Toxic–Irritant and Immunoglobulin E‐Mediated Endotypes, Diagnosis and Management

Clinical &Experimental Allergy, EarlyView.
Most reactions are toxic–irritant, driven by epithelial injury and neuro‐inflammatory activation. IgE‐mediated allergy is less common but may cause immediate systemic reactions. Endotype differentiation guides diagnosis, risk stratification and management.
Prasad Dasari, Josefine Haas, Wolfgang Rohe, Kai Gloyna, Christoph Viebahn, Susann Forkel, Michael Szardenings, Christine Stadelmann, Michael P. Schön, Timo Buhl   +9 more
wiley   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, EarlyView.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source