Results 51 to 60 of about 462,419 (289)

Student's $t$-test for scale mixture errors

, 2006
Generalized t-tests are constructed under weaker than normal conditions. In the first part of this paper we assume only the symmetry (around zero) of the error distribution (i). In the second part we assume that the error distribution is a Gaussian scale
Székely, Gábor J.
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Estimation of the percentile of Birnbaum-Saunders distribution and its application to PM2.5 in Northern Thailand [PDF]

PeerJ
The Birnbaum-Saunders distribution plays a crucial role in statistical analysis, serving as a model for failure time distribution in engineering and the distribution of particulate matter 2.5 (PM2.5) in environmental sciences.
Warisa Thangjai, Sa-Aat Niwitpong, Suparat Niwitpong   +2 more
doaj   +2 more sources

Estimation of Stress-Strength model in the Generalized Linear Failure Rate Distribution [PDF]

, 2013
In this paper, we study the estimation of $R=P [Y < X ]$, also so-called the stress-strength model, when both $X$ and $Y$ are two independent random variables with the generalized linear failure rate distributions, under different assumptions about their
Daneshkhah, Alireza, Shahsanaei, Fatemeh
core  

Metrology and 1/f noise: linear regressions and confidence intervals in flicker noise context [PDF]

, 2015
1/f noise is very common but is difficult to handle in a metrological way. After having recalled the main characteristics of stongly correlated noise, this paper will determine relationships giving confidence intervals over the arithmetic mean and the ...
Lantz, Eric, Vernotte, Francois
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Confidence Intervals for Two Proportions—A Generalized Estimation and Information Assessment

Mathematics
This paper develops profile score confidence intervals (i.e., z-standard intervals) by inverting orthogonalized score estimators for comparing two independent binomial proportions in rate difference, rate ratio, or odds ratio and utilizes a generalized ...
Qiang Wu, Paul Vos
doaj   +1 more source

Confidence Intervals for Mean and Difference between Means of Normal Distributions with Unknown Coefficients of Variation

Mathematics, 2017
This paper proposes confidence intervals for a single mean and difference of two means of normal distributions with unknown coefficients of variation (CVs).
Warisa Thangjai, Suparat Niwitpong, Sa-Aat Niwitpong   +2 more
doaj   +1 more source