Results 41 to 50 of about 369,068 (270)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Effect of motivational interviewing on treatment adherence and self‐efficacy of adolescents with asthma: A randomized controlled trial

open access: yesNursing Open, 2023
Aims This study examined the short‐term effect of motivational interviewing on treatment adherence and self‐efficacy of adolescents with asthma. Design The randomized controlled trial.
Fatemeh Taheri   +3 more
doaj   +1 more source

Semiparametric binary model for clustered survival data [PDF]

open access: yes, 2014
This paper considers a method to analyze semiparametric binary models for clustered survival data when the responses are correlated. We extend parametric generalized estimating equation (GEE) to semiparametric GEE by introducing smoothing spline into the
Abu Bakar, Mohd Rizam   +3 more
core   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Three-year outcomes of vitrectomy combined with intraoperative dexamethasone implantation for non-tractional refractory diabetic macular edema

open access: yesScientific Reports, 2021
This retrospective, consecutive interventional study investigated the long-term clinical outcomes of combined vitrectomy with intraoperative dexamethasone implants for non-tractional refractory diabetic macular edema (DME).
Sungsoon Hwang   +4 more
doaj   +1 more source

Semiparametric Multivariate Accelerated Failure Time Model with Generalized Estimating Equations

open access: yes, 2012
The semiparametric accelerated failure time model is not as widely used as the Cox relative risk model mainly due to computational difficulties. Recent developments in least squares estimation and induced smoothing estimating equations provide promising ...
A Komárek   +40 more
core   +1 more source

Exam‐level analysis of lecture capture viewing and student exam performance

open access: yesFEBS Open Bio, EarlyView.
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley   +1 more source

Associations between self-efficacy and health-related quality of life in haemorrhagic stroke survivors: a longitudinal study

open access: yesBMC Public Health
Background The impact of recovery self-efficacy on health-related quality of life in haemorrhagic stroke survivors remains unclear. This longitudinal study examined this association through a one-year follow-up after discharge.
Wei Zhu   +4 more
doaj   +1 more source

A new solid particle erosion model for oriented fiber composite materials [PDF]

open access: yes, 2014
The work describes a new model of erosion estimation equation which factors in both the impingement angle α and the fiber orientation angle β. Two examples of particular erosion equations are presented, for carbon fiber as well as for glass fiber in ...
Danuta GRAD, Valeriu DRAGAN
core   +1 more source

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler   +43 more
wiley   +1 more source

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