Results 41 to 50 of about 53,669 (252)

Assessment of a Modified Sandwich Estimator for Generalized Estimating Equations with Application to Opioid Poisoning in MIMIC-IV ICU Patients

open access: yesStats, 2021
Longitudinal data is encountered frequently in many healthcare research areas to include the critical care environment. Repeated measures from the same subject are expected to correlate with each other.
Paul Rogers, Julie Stoner
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Evaluation of Bipolar Disorder in Several Recurrences over the Time Using Generalized Estimating Equations

open access: yesIranian Journal of Psychiatry, 2017
Objective: Bipolar disorder is characterized by periods of manic, depression, or mixed episodes. The purpose of this study was to assess the development of bipolar disorder episode over the time as well as determining the risk factors affecting bipolar ...
Payam Amini   +3 more
doaj  

Associations between self-efficacy and health-related quality of life in haemorrhagic stroke survivors: a longitudinal study

open access: yesBMC Public Health
Background The impact of recovery self-efficacy on health-related quality of life in haemorrhagic stroke survivors remains unclear. This longitudinal study examined this association through a one-year follow-up after discharge.
Wei Zhu   +4 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

Exclusive breastfeeding until six months of age and its influence on anthropometric indices: A prospective observational study

open access: yesAsian Journal of Medical Sciences
Background: The WHO recommends exclusive breastfeeding (EBF) for the first 6 months of life, for all infants; and prescribes WHO Multicentre Growth Reference Study charts for growth monitoring.
Asha Jyothi Penugonda   +6 more
doaj   +1 more source

Non-Linear Langevin and Fractional Fokker–Planck Equations for Anomalous Diffusion by Lévy Stable Processes

open access: yesEntropy, 2018
The numerical solutions to a non-linear Fractional Fokker–Planck (FFP) equation are studied estimating the generalized diffusion coefficients. The aim is to model anomalous diffusion using an FFP description with fractional velocity derivatives and
Johan Anderson, Sara Moradi, Tariq Rafiq
doaj   +1 more source

Stagewise Generalized Estimating Equations with Grouped Variables

open access: yesBiometrics, 2017
SummaryForward stagewise estimation is a revived slow-brewing approach for model building that is particularly attractive in dealing with complex data structures for both its computational efficiency and its intrinsic connections with penalized estimation.
Vaughan, Gregory   +3 more
openaire   +3 more sources

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

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