Results 41 to 50 of about 376,287 (286)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Goodness-of-Fit and Generalized Estimating Equation Methods for Ordinal Responses Based on the Stereotype Model

Stats, 2022
Background: Data with ordinal categories occur in many diverse areas, but methodologies for modeling ordinal data lag severely behind equivalent methodologies for continuous data.
Daniel Fernández, Louise McMillan, Richard Arnold, Martin Spiess, Ivy Liu   +4 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Empirical Likelihood and General Estimating Equations

The Annals of Statistics, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Qin, Jin, Lawless, Jerry
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Evaluation of Bipolar Disorder in Several Recurrences over the Time Using Generalized Estimating Equations

Iranian Journal of Psychiatry, 2017
Objective: Bipolar disorder is characterized by periods of manic, depression, or mixed episodes. The purpose of this study was to assess the development of bipolar disorder episode over the time as well as determining the risk factors affecting bipolar ...
Payam Amini, Roya Najafi-Vosough, Ali Ghaleiha, hossein mahjub   +3 more
doaj  

Fused kernel-spline smoothing for repeatedly measured outcomes in a generalized partially linear model with functional single index

, 2015
We propose a generalized partially linear functional single index risk score model for repeatedly measured outcomes where the index itself is a function of time.
Jiang, Fei, Ma, Yanyuan, Wang, Yuanjia
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Associations between self-efficacy and health-related quality of life in haemorrhagic stroke survivors: a longitudinal study

BMC Public Health
Background The impact of recovery self-efficacy on health-related quality of life in haemorrhagic stroke survivors remains unclear. This longitudinal study examined this association through a one-year follow-up after discharge.
Wei Zhu, Qiaoyu Yang, Baoyue Zhang, Cong Wang, Chaofeng Fan   +4 more
doaj   +1 more source

Effect of motivational interviewing on treatment adherence and self‐efficacy of adolescents with asthma: A randomized controlled trial

Nursing Open, 2023
Aims This study examined the short‐term effect of motivational interviewing on treatment adherence and self‐efficacy of adolescents with asthma. Design The randomized controlled trial.
Fatemeh Taheri, Ahmad Nasiri, Somayeh Namdari, Fatemeh Salmani   +3 more
doaj   +1 more source