Results 21 to 30 of about 57,522 (246)

Intrinsic Network Brain Dysfunction Correlates With Temporal Complexity in Generalized Anxiety Disorder and Panic Disorder

Frontiers in Human Neuroscience, 2021
Background: Generalized anxiety disorder (GAD) and panic disorder (PD) are the two severe subtypes of anxiety disorders (ADs), which are similar in clinical manifestation, pathogenesis, and treatment.
Li Xu, Li Xu, Huazhen Xu, Huachen Ding, Jinyang Li, Chun Wang, Chun Wang, Chun Wang, Chun Wang   +8 more
doaj   +1 more source

Functional Network Connectivity Patterns between Idiopathic Generalized Epilepsy with Myoclonic and Absence Seizures

Frontiers in Computational Neuroscience, 2017
The extensive cerebral cortex and subcortical structures are considered as the major regions related to the generalized epileptiform discharges in idiopathic generalized epilepsy.
Qifu Li, Qifu Li, Yongmin Chen, Yong Wei, Shengmei Chen, Lin Ma, Zhiyi He, Zhibin Chen   +7 more
doaj   +1 more source

Generalized torsion elements in groups.

, 2023
A group element is called a generalized torsion element if a finite product of its conjugates is equal to the identity. We prove that in a nilpotent or FC-group, the generalized torsion elements are all torsion elements.
Bastos Júnior, Raimundo de Araújo, Silveira, Danilo Sanção da, Schneider, Csaba   +2 more
core   +1 more source

The Tits alternative for non-spherical Pride groups [PDF]

, 2008
Pride groups, or 'groups given by presentations in which each defining relator involves at most two types of generators', include Coxeter groups, Artin groups, triangles of groups, and Vinberg's groups defined by periodic paired relations.
Williams, Gerald, Natalia Kopteva, Kopteva, Natalia, Kopteva, N, Gerald Williams, Williams, G   +5 more
core   +1 more source

Amalgamated Generalized Low Density Parity Check and Luby Transform Codes for the Wireless Internet [PDF]

, 2007
Luby Transform codes (LT) were originally designed for the Binary Erasure Channel (BEC) encountered owing to randomly dropped packets in the statistical multiplexing aided Internet, where transmitted packets are not affected by the fading or noise of the
T. D. Nguyen, L. L. Yang, FC. Kuo, Guo, F.C., L. Hanzo, Yang, L-L., Nguyen, T.D., Hanzo, L.   +7 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

All Finite Generalized Tetrahedron Groups [PDF]

, 2008
A generalized tetrahedron groups is defined to be a group admitting a presentation where l,m,n,p,q,r >= 2, each W_i(a,b) is a cyclically reduced word involving both a and b.
Scheer, Martin, Hulpke, Alexander, Rebel, Volker große, Rosenberger, Gerhard, Fine, Benjamin, Hahn, Miriam   +5 more
core   +1 more source