Results 51 to 60 of about 6,245,235 (232)

Cell-Selective Delivery of RIBOTACs via an Anti-EGFR Nanobody for Pancreatic Cancer Treatment. [PDF]

Adv Sci (Weinh)
This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Luo T, Wang Y, Chen D, Zhang Y, Shuai Y, Yao H, Jiang T, Jiang H, Zhong M, Wang X, Wang Z, Xu C, Goel A, Ma HT, Gao F, Wang X.   +15 more
europepmc   +2 more sources

Yhteistyökumppanuudesta saatavat hyödyt : Case: FC Lahti Oy [PDF]

, 2020
Opinnäytetyön tavoitteena oli tutkia FC Lahden yhteistyökumppaneiden saamia hyötyjä yhteistyöstä. Lisäksi tutkimuksella haluttiin selvittää vuoden 2019 yhteistyökumppaneiden motiiveja, kokemuksia sekä tyytyväisyyttä yhteistyöstä FC Lahden kanssa ...
Kantanen, Teemu, Kokkonen, Simo
core  

When Poor Exciton Dissociation Limits Photocurrents in Organic Solar Cells: Why Low Offset Non‐Fullerene Acceptor Blends Can't Be Efficient

Advanced Materials, EarlyView.
The energetic offset between the donor and the acceptor components in organic photoactive layers is central to the tradeoff between photovoltage and photocurrent losses. This Perspective covers the most important issues surrounding this topic in non‐fullerene acceptor blends, from the difficulty of accurately determining state energies and driving ...
Dieter Neher, Manasi Pranav
wiley   +1 more source

Unveiling Exsolution‐Induced Giant Electronic and Magnetic Property Changes in Non‐Stoichiometric Titanate Perovskite Thin Films

Advanced Materials, EarlyView.
A giant insulator to metal transition and emergent superparamagnetism are revealed by nanoparticle exsolution in non‐stoichiometric titanate perovskite thin films. By combining transport, synchrotron spectroscopy, and first‐principles calculations, this work reveals how defect reconfiguration and lattice reconstruction fundamentally reshape electronic ...
Sungil Kim, June Ho Lee, Yaolong Xing, Dongchang Kim, Haeseong Jeong, Mongjun Jeong, Manuel Valvidares, Stuart S. P. Parkin, Sang Ho Oh, Donghwa Lee, Hyojin Yoon, Hyeon Han   +11 more
wiley   +1 more source

Multivariate analysis of Côte d’Ivoire consumer price index: linear, regularized and generalized regression approaches

Discover Analytics
The high cost of living is a major challenge for Ivorian consumers. This paper seeks to explain this issue using Principal Component Analysis (PCA), Hierarchical Ascending Classification (HAC), as well as linear, regularized (Lasso, Ridge, Elastic Net ...
Aubin Yao N’Dri, Auguste Konan Kouakou, Amadou Kamagaté, Ouagnina Hili   +3 more
doaj   +1 more source

Predicting the Reliability of Steel Ropes at the Design Stage

Безопасность техногенных и природных систем
Introduction. Ensuring the safety of lifting equipment is closely linked to the reliability of steel ropes operating under variable loads and in aggressive environments.
A. A. Kotesov
doaj   +1 more source

A Geometrically Transient Platform for Bioelectronic Implants

Advanced Materials, EarlyView.
Minimally invasive bioelectronic implants often compromise performance for smaller sizes. To resolve this optimization dilemma, a wireless bioelectronic implant with a transient geometry is introduced (MiFi). The origami‐inspired device miniaturizes up to sixfold for syringe insertion and autonomously unfolds post‐implantation.
Selin Olenik, John D. Goodwin, Atharv Naik, Philip Coatsworth, Ioi Chit Cheung, Farbod Amirghasemi, Anies Sohi, Ehsan Abedi, Tayeb Tadlaoui, Maral P. S. Mousavi, Andriy S. Kozlov, Victoria Salem, Andrew S. Cowburn, Firat Guder   +13 more
wiley   +1 more source

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

Advanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte, Benjamin E. Nachod, Julia Baena, Jenna Muscat‐Rivera, Lesley Chaboub, Hannah C. Safford, Hannah C. Geisler, Hannah M. Yamagata, Melgious J. Y. Ang, Michael Kegel, Alexandre Poirier, Elaine R. Tong, Zhe Zhong, Qiangqiang Shi, Jinjin Wang, Elisa Battistini, Ye Zeng, Alex G. Hamilton, Kelsey L. Swingle, Drew Weissman, Jilian R. Melamed, Michael J. Mitchell   +21 more
wiley   +1 more source

Generalized core spanner inexpressibility via Ehrenfeucht-Fraïssé games for FC

Despite considerable research on document spanners, little is known about the expressive power of generalized core spanners. In this paper, we use Ehrenfeucht-Fraïssé games to obtain general inexpressibility lemmas for the logic FC (a finite model ...
Sam Thompson (13886418), Dominik Freydenberger (3718891)   +1 more
core   +5 more sources

The Tits alternative for non-spherical Pride groups [PDF]

, 2008
Pride groups, or 'groups given by presentations in which each defining relator involves at most two types of generators', include Coxeter groups, Artin groups, triangles of groups, and Vinberg's groups defined by periodic paired relations.
Williams, Gerald, Natalia Kopteva, Kopteva, Natalia, Kopteva, N, Gerald Williams, Williams, G   +5 more
core   +1 more source