Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Generalized Additive Modeling of Ecological Data With mgcv: New Adequacy Assessment Tools. [PDF]
Mainguy J +5 more
europepmc +1 more source
ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray +3 more
wiley +1 more source
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv +11 more
wiley +1 more source
Full-cycle prediction of crack healing in self-healing concrete using generalized polynomial chaos expansion. [PDF]
Fu C +6 more
europepmc +1 more source
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng +17 more
wiley +1 more source
Research and Implementation of Localization of Multiple Local Discharge Sources in Switchgear Based on Ultrasound. [PDF]
Xu D +7 more
europepmc +1 more source
Discovering Interpretable Semantics from Radio Signals for Contactless Cardiac Monitoring
This study presents a semantic representation framework for clinically interpretable cardiac monitoring from contactless radio signals. It formulates radio semantic learning as an information‐bottleneck problem and approximates the objective via intra‐modal compression and cross‐modal alignment, structuring radio measurements into meaningful semantic ...
Jinbo Chen +10 more
wiley +1 more source
Generalized 3D quasi-phase-matching model of image contrast in second harmonic generation microscopy of fibrillar collagen architectures. [PDF]
Shelton EM, Campagnola PJ.
europepmc +1 more source
MGDP: Mastering a Generalized Depth Perception Model for Quadruped Locomotion
ABSTRACT Perception‐based Deep Reinforcement Learning (DRL) controllers demonstrate impressive performance on challenging terrains. However, existing controllers still face core limitations, struggling to achieve both terrain generality and platform transferability, and are constrained by high computational overhead and sensitivity to sensor noise.
Yinzhao Dong +9 more
wiley +1 more source

