Results 71 to 80 of about 2,191,147 (178)

Transcriptome-Wide Expression Profiling in Skin Fibroblasts of Patients with Joint Hypermobility Syndrome/Ehlers-Danlos Syndrome Hypermobility Type. [PDF]

PLoS ONE, 2016
Joint hypermobility syndrome/Ehlers-Danlos syndrome hypermobility type (JHS/EDS-HT), is likely the most common systemic heritable connective tissue disorder, and is mostly recognized by generalized joint hypermobility, joint instability complications ...
Nicola Chiarelli, Giulia Carini, Nicoletta Zoppi, Chiara Dordoni, Marco Ritelli, Marina Venturini, Marco Castori, Marina Colombi   +7 more
doaj   +1 more source

Quality of Online Information for Management of Leg Pain in Children and Adolescents With Hypermobility‐Associated Conditions

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Online health information seeking continues to gain popularity. Quality assessment of online information is particularly important for patient populations with low satisfaction and disengagement from health professionals and services, such as hypermobility‐associated conditions.
R. Quinlan, V. Pacey, R. Thomas, K. Gray, L. M. Davies   +4 more
wiley   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Hypermobility Is a Risk Factor for Nonoperative Treatment Failure in Scapholunate Ligament Injury

Plastic and Reconstructive Surgery, Global Open
Background:. Generalized joint hypermobility, defined by the Beighton score, is typically associated with poor outcomes after large ligament injury. However, its impact on scapholunate interosseous ligament (SLIL) injuries remains unknown. Methods:.
Timothy P. Liu, MD, Nirbhay S. Jain, MD, Christopher Pham, MD, Jeremiah M. Taylor, MD, Jose M. Chevalier, BS, Kodi K. Azari, MD   +5 more
doaj   +1 more source

Ocular and Systemic Findings in COL2A1 and COL11A1 Stickler Syndrome

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2656-2664, December 2026.
ABSTRACT Stickler syndrome is most commonly caused by variants in COL2A1 and COL11A1 genes. The purpose of this study was to describe genetic variants and phenotypes in COL2A1 and COL11A1 Stickler syndrome. We performed a retrospective genotype–phenotype evaluation of COL2A1 and COL11A1 Stickler syndrome subjects. Thirty‐two subjects with COL2A1 and 13
Aileen G. MacLachlan, Jessica A. Kraker, Denise J. Morgan, Lisa A. Schimmenti, M. Elizabeth Hartnett, Eileen S. Hwang   +5 more
wiley   +1 more source

Editorial Commentary: Patients With Generalized Ligamentous Laxity Recover Slower and Have More Pain but Eventually Achieve Good Outcomes: A Key Message in Preoperative Counseling!

Arthroscopy, Volume 42, Issue 11, Page 2575-2576, November 2026.
Abstract Patients with generalized ligamentous laxity undergoing hip arthroscopy have traditionally been challenging for hip arthroscopists when setting preoperative expectations. Recent literature confirms slower recovery, increased pain, and worse patient‐reported outcomes in the near postoperative period before ultimate normalization in the midterm,
Riley Hemstock, Moin Khan
wiley   +1 more source

The distribution of hypermobile joint mobility tests in the eight combinations to define generalized joint hypermobility.

The distribution of hypermobile joint mobility tests in the eight combinations to define generalized joint hypermobility.
Christina B. Olsson (17140285), Lena Nilsson-Wikmar (5863346), Per Kristiansson (707526), Angela Schlager (5863340), Kerstin Ahlqvist (5863343)   +4 more
core   +1 more source

Beyond Joint Hypermobility: Investigating Bladder Dysfunction in Hypermobile Ehlers‐Danlos Syndrome

Neurourology and Urodynamics, Volume 45, Issue 8, Page 1687-1691, November 2026.
ABSTRACT Introduction and Objectives Hypermobile Ehlers‐Danlos Syndrome (hEDS) is the most common subtype of Ehlers‐Danlos Syndrome, a group of connective tissue disorders caused by collagen abnormalities. While musculoskeletal features of hEDS are well characterized, its impact on visceral organs, including the bladder, remains underexplored.
Marium Ansari, Mallory Pine, Viktoriya Sapkalova, Emily Chan Brodowsky, Charles R. Powell, Ramzy T. Burns   +5 more
wiley   +1 more source

Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2396-2404, October 2026.
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley   +1 more source

An Analysis of Generalized Joint Hypermobility and Knee Pathology [PDF]

, 1998
The purpose of this study is to evaluate if a relationship exists between generalized joint syndrome and knee pathology. Both of these have been found to be of increased prevalence in females.
Gustafson, Jan L.
core   +1 more source