SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Precisiones en la teoría de los modelos logísticos
Revista Colombiana de Estadística, 2006 Se estudian los modelos logísticos, como una clase de modelos lineales generalizados (MLG). Se demuestra un teorema sobre la existencia y unicidad de las estimaciones de máxima verosimilitud (abreviadas por ML) de los parámetros logísticos y el método ...
HUMBERTO JESÚS LLINÁS
doaj
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Erratum: A Poisson generalized linear model application to disentangle the effects of various parameters on neurophysiological discharges. [PDF]
STAR Protoc, 2021 Vaccari FE +4 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source
A retrospective study of environmental predictors of dengue in Delhi from 2015 to 2018 using the generalized linear model. [PDF]
Sci Rep, 2022 Singh PS, Chaturvedi HK.
europepmc +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Evaluation of multiple linear regression function and generalized linear model types in estimating natural menopausal age: A cross-sectional study. [PDF]
Int J Reprod Biomed, 2022 Sadeghi N +4 more
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Exploring the Association between Compliance with Measures to Prevent the Spread of COVID-19 and Big Five Traits with Bayesian Generalized Linear Model [PDF]
Pers Individ Dif, 2021 Han H.
europepmc +2 more sources