Results 41 to 50 of about 1,282,217 (275)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Generalized linear models

, 2002
Abstract While this model is important for normally distributed data, it is less useful for other distributions such as the binomial, Poisson and gamma. The context in which such distributions are used often means that we need to model E [Y ] as a non-linear function of Xβ .
Paul Garthwaite, Ian Jolliffe, Byron Jones   +2 more
openaire   +4 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Why analyze germination experiments using Generalized Linear Models?

Journal of Seed Science
: We compared the goodness of fit and efficiency of models for germination. Generalized Linear Models (GLMs) were performed with a randomized component corresponding to the percentage of germination for a normal distribution or to the number of ...
Fábio Janoni Carvalho, Denise Garcia de Santana, Lúcio Borges de Araújo   +2 more
doaj   +1 more source

A Note on the Identifiability of Generalized Linear Mixed Models [PDF]

, 2014
I present here a simple proof that, under general regularity conditions, the standard parametrization of generalized linear mixed model is identifiable.
Labouriau, Rodrigo
core  

Mixtures of g-priors in Generalized Linear Models

, 2018
Mixtures of Zellner's g-priors have been studied extensively in linear models and have been shown to have numerous desirable properties for Bayesian variable selection and model averaging. Several extensions of g-priors to Generalized Linear Models (GLMs)
Clyde, Merlise A., Li, Yingbo
core   +2 more sources

Sparsifying Generalized Linear Models

Proceedings of the 56th Annual ACM Symposium on Theory of Computing
We consider the sparsification of sums $F : \mathbb{R}^n \to \mathbb{R}$ where $F(x) = f_1(\langle a_1,x\rangle) + \cdots + f_m(\langle a_m,x\rangle)$ for vectors $a_1,\ldots,a_m \in \mathbb{R}^n$ and functions $f_1,\ldots,f_m : \mathbb{R} \to \mathbb{R}_+$.
Arun Jambulapati, James R. Lee, Yang P. Liu, Aaron Sidford   +3 more
openaire   +2 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Generalized linear models

, 2015
AbstractGeneralized Linear Modeling (GLM) unifies several statistical techniques, providing a stable and modular foundation on which to build a useful working knowledge of statistical modeling. GLMs enable a re-interpretation of previously learned ANOVA and regression techniques and integrate well with more advanced modeling techniques introduced in ...
  +6 more sources