Results 31 to 40 of about 927,204 (249)
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Construction of optimal multi-level supersaturated designs
, 2006 A supersaturated design is a design whose run size is not large enough for estimating all the main effects. The goodness of multi-level supersaturated designs can be judged by the generalized minimum aberration criterion proposed by Xu and Wu [Ann ...
Wu, C. F. J., Xu, Hongquan
core +1 more source
Analysis and interpretation of the Seidel aberration coefficients in digital holography [PDF]
, 2011 Peer reviewedPublisher ...
Champagne +10 more
core +1 more source
Invariance of generalized wordlength patterns
, 2008 The generalized wordlength pattern (GWLP) introduced by Xu and Wu (2001) for an arbitrary fractional factorial design allows one to extend the use of the minimum aberration criterion to such designs. Ai and Zhang (2004) defined the $J$-characteristics of
Beder, Jay H., Willenbring, Jeb F.
core +2 more sources
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Diffractive X-ray Telescopes [PDF]
, 2010 Diffractive X-ray telescopes using zone plates, phase Fresnel lenses, or related optical elements have the potential to provide astronomers with true imaging capability with resolution several orders of magnitude better than available in any other ...
Skinner, Gerald K.
core +3 more sources
Active optics: deformable mirrors with a minimum number of actuators [PDF]
Journal of the European Optical Society, Volume 7, 12036, 2012, 2012 We present two concepts of deformable mirror to compensate for first order optical aberrations. Deformation systems are designed using both elasticity theory and Finite Element Analysis in order to minimize the number of actuators. Starting from instrument specifications, we explain the methodology to design dedicated deformable mirrors.
arxiv +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Complete enumeration of two-Level orthogonal arrays of strength $d$ with $d+2$ constraints
, 2007 Enumerating nonisomorphic orthogonal arrays is an important, yet very difficult, problem. Although orthogonal arrays with a specified set of parameters have been enumerated in a number of cases, general results are extremely rare.
Stufken, John, Tang, Boxin
core +2 more sources