Results 41 to 50 of about 927,204 (249)

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

HoloTrap: Interactive hologram design for multiple dynamic optical trapping [PDF]

, 2006
This work presents an application that generates real-time holograms to be displayed on a holographic optical tweezers setup; a technique that allows the manipulation of particles in the range from micrometres to nanometres.
A. Carnicer, Ashkin, Curtis, E. Martín-Badosa, E. Pleguezuelos, Gerchberg, Goodman, J. Andilla, Leach, Liesener, M. Montes-Usategui, Martín-Badosa, Montes-Usategui, Neuman, Polin, Prentice, Reicherter, Rodrigo, Roichman, Seldowitz, Sinclair, Soifer, Tao, Tudela, Tudela, Whyte   +25 more
core   +3 more sources

The Long Term Effects of a 12‐Session Community Exercise Program on Health Measures in Cancer Patients

Aging and Cancer, EarlyView.
ABSTRACT Purpose To assess the long‐term effects of a community cancer exercise program on quality of life, fatigue, weight, waist circumference, physical activity levels, lower extremity strength, body mass index (BMI), heart rate, and blood pressure, across non‐metastatic and metastatic patients.
Isaac Oppong, Roozbeh Naemi
wiley   +1 more source

High-contrast imaging at small separation: impact of the optical configuration of two deformable mirrors on dark holes [PDF]

, 2017
The direct detection and characterization of exoplanets will be a major scientific driver over the next decade, involving the development of very large telescopes and requires high-contrast imaging close to the optical axis.
Abe, L., Baudoz, P., Beaulieu, M., Gouvret, C., Martinez, P., Vakili, F.   +5 more
core   +2 more sources

Calibration-free quantitative phase imaging using data-driven aberration modeling [PDF]

, 2020
We present a data-driven approach to compensate for optical aberration in calibration-free quantitative phase imaging (QPI). Unlike existing methods that require additional measurements or a background region to correct aberrations, we exploit deep learning techniques to model the physics of aberration in an imaging system.
arxiv   +1 more source

Modelling of a double‐scattering proton therapy nozzle using the FLUKA Monte Carlo code and analysis of linear energy transfer in patients treated for prostate cancer

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The dose‐averaged linear energy transfer (LETD) in proton therapy (PT) has in pre‐clinical studies been linked to the relative biological effectiveness (RBE) of protons. Until recently, the most common PT delivery method in prostate cancer has been double‐scattered PT, with LETD only available through dedicated Monte Carlo (MC ...
Rasmus Klitgaard, Lars Fredrik Fjæra, Camilla Hanquist Stokkevåg, Perry Johnson, Mark Artz, Nancy Price Mendenhall, Curtis Bryant, Ludvig Paul Muren   +7 more
wiley   +1 more source

Improving holographic particle characterization by modeling spherical aberration [PDF]

arXiv, 2021
Holographic microscopy combined with forward modeling and inference allows colloidal particles to be characterized and tracked in three dimensions with high precision. However, current models ignore the effects of optical aberrations on hologram formation.
arxiv  

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

Aberration and the Speed of Gravity [PDF]

Phys.Lett.A267:81-87,2000, 1999
The observed absence of gravitational aberration requires that ``Newtonian'' gravity propagate at a speed $c_g>2\times10^{10}c$. By evaluating the gravitational effect of an accelerating mass, I show that aberration in general relativity is almost exactly canceled by velocity-dependent interactions, permitting $c_g=c$.
arxiv   +1 more source

Comprehensive clinical evaluation of novel 4DCT‐based lung function imaging methods

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Methods have been developed that apply image processing to 4DCTs to generate 4DCT‐ventilation/perfusion lung imaging. Traditional methods for 4DCT‐ventilation rely on Hounsfield‐Unit (HU) density‐change methods and suffer from poor numerical robustness while not providing 4DCT‐perfusion data.
Ehsan Golkar, Taindra Neupane, Lydia Wilson, Jennifer Kwak, Richard Castillo, Edward Castillo, Yevgeniy Vinogradskiy   +6 more
wiley   +1 more source