Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton +13 more
wiley +1 more source
Doubly Robust Estimation and Sensitivity Analysis With Outcomes Truncated by Death in Multi-Arm Clinical Trials. [PDF]
Tong J +4 more
europepmc +1 more source
NiNb alloys enable efficient charge‐to‐spin conversion by combining the spin Hall effect of nickel with the orbital Hall effect of niobium. Composition tuning yields spin‐torque efficiencies of −1.4 to −1.7 and a non‐monotonic efficiency‐resistivity relationship, revealing orbital‐spin synergy beyond conventional spin Hall materials and offering a ...
Chuangwen Wu +16 more
wiley +1 more source
A Stroke of Insight? Possible Bidirectional Relationship Between Stroke and Epilepsy. [PDF]
Terman SW.
europepmc +1 more source
Data‐Driven Discovery of Unconventional Antiferromagnets
A high‐throughput workflow that combines the physics‐informed pre‐screening, high‐throughput exchange calculations, Luttinger‐Tisza analysis and symmetry classification is established for accurate identification of unconventional antiferromagnets from the broad structural database.
Qirui Cui +3 more
wiley +1 more source
A marginal structural model for normal tissue complication probability. [PDF]
Tang TS +4 more
europepmc +1 more source
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
Estimating Baseline Survival Function in the Proportional Hazards Model Under Monotone Hazards. [PDF]
Wu Y, Chappell R.
europepmc +1 more source
Physics‐Aware Machine‐Learning‐Driven Inverse Design of Broadband Ultra‐Open Acoustic Metamaterials
A physics‐aware machine‐learning framework enables inverse design of ultra‐open acoustic silencers by decoupling spectral and radial design spaces. The approach rapidly identifies broadband, compact, and highly ventilated architectures, while revealing hidden linear design rules that link geometry, impedance matching, and acoustic performance.
Zhiwei Yang +5 more
wiley +1 more source
From Linear Geometry to Nonlinear and Information-Geometric Settings in Test Theory: Bregman Projections as a Unifying Framework. [PDF]
Zumbo BD.
europepmc +1 more source

