Results 151 to 160 of about 4,743 (301)

Validation of the Korean Version of the Meta-Worry Questionnaire Among the General Population. [PDF]

Psychiatry Investig
Lee HS, Shahrier MA, Yoo S, Chung S.
europepmc   +1 more source

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

A Generalized Fisher Discriminant Analysis with Adaptive Entropic Regularization for Cross-Model Vibration State Monitoring in Wind Tunnels. [PDF]

Sensors (Basel)
Li Z, Li Z, Chen X, Lin H.
europepmc   +1 more source

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

Analysis of delay differential equations with dual caputo-type fractional derivatives using laplace transform methods. [PDF]

Sci Rep
Boumaaza M, Boutiara A, Djidel O, Guefaifia R, Boulaaras S.   +4 more
europepmc   +1 more source

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

Advanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang, Liqin Zhou, Rong Wang, Yuehua Han, Zhentao Zuo, Yanghua Tian, Ke Zhou   +6 more
wiley   +1 more source

MonotonicityTest: An R Package for Efficient Nonparametric Monotonicity Testing. [PDF]

Obs Stud
Huynh D, Parast L.
europepmc   +1 more source

Backbone‐Length‐Optimized Inhibitors Deliver Long‐Retention Selectivity in Area‐Selective ALD of VO2

Advanced Science, EarlyView.
Area‐selective VO2 ALD is found to depend critically on inhibitor backbone length, which governs physisorption, chemisorption stability, and packing efficiency in a coupled manner. An intermediate backbone‐length achieves the best long‐retention selectivity, establishing a chemically and geometrically grounded design principle for small‐molecule ...
Hae Lin Yang, Eun Chong Cho, Minchan Kim, Hye In Park, Ga‐young Lee, Seunghwan Lee, Beomseok Kim, Changhwa Jung, Youngkwon Kim, Jin‐Seong Park   +9 more
wiley   +1 more source

The Theoretical Regularity Properties of the Normalized Quadratic Consumer Demand Model [PDF]

We conduct a Monte Carlo study of the global regularity properties of the Normalized Quadratic model. We particularly investigate monotonicity violations, as well as the performance of methods of locally and globally imposing curvature.
William Barnett, Ikuyasu Usui
core  

A Stroke of Insight? Possible Bidirectional Relationship Between Stroke and Epilepsy. [PDF]

Epilepsy Curr
Terman SW.
europepmc   +1 more source