Results 41 to 50 of about 30,221 (235)

Cost Optimization of AC Microgrids in Grid-Connected and Isolated Modes Using a Population-Based Genetic Algorithm for Energy Management of Distributed Wind Turbines

Mathematics
This research investigates the effectiveness of four metaheuristic algorithms, the Population-Based Genetic Algorithm, Particle Swarm Optimization, JAYA, and Generalized Normal Distribution Optimizer, for managing the energy production of wind-based ...
Luis Fernando Grisales-Noreña, Héctor Pinto Vega, Oscar Danilo Montoya, Vanessa Botero-Gómez, Daniel Sanin-Villa   +4 more
doaj   +1 more source

The Deep Weight Prior [PDF]

, 2019
Bayesian inference is known to provide a general framework for incorporating prior knowledge or specific properties into machine learning models via carefully choosing a prior distribution.
Ashukha, Arsenii, Atanov, Andrei, Struminsky, Kirill, Vetrov, Dmitry, Welling, Max   +4 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Algorithm and performance of a clinical IMRT beam-angle optimization system

, 2003
This paper describes the algorithm and examines the performance of an IMRT beam-angle optimization (BAO) system. In this algorithm successive sets of beam angles are selected from a set of predefined directions using a fast simulated annealing (FSA ...
Bortfeld T, Bortfeld T Stein J Preiser K, Braunstein M, Chuang K S, Crooks S M, Das S, David Djajaputra, Geman S, Jackson A, Kirkpatrick S, Llacer J, Mageras G S, Metropolis N, Oldham M, Pugachev A, Pugachev A B, Qiuwen Wu, Radhe Mohan, Rowbottom C G, Rowbottom C G, Rowbottom C G, Spirou S V, Stein J, Webb S, Webb S, Wu Q, Wu Q, Xiang Y, Xing L, Yan Wu   +29 more
core   +1 more source

ESTIMATION AND OPTIMAL PLANS OF MULTIPLE RAMP-STRESS ACCELERATED LIFE TESTS FOR THE GENERALIZED HALF-NORMAL DISTRIBUTION [PDF]

Journal of the Egyptian Mathematical Society, 2018
Accelerated life tests are commonly utilized in manufacturing industries to induce early failures of highly reliableproducts. In this paper, estimation and optimal design issues of multiple ramp-stress accelerated life tests are discussedfor the generalized half-normal distribution.
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Intelligent Active and Reactive Power Management for Wind-Based Distributed Generation in Microgrids via Advanced Metaheuristic Optimization

Applied System Innovation
This research evaluates the performance of six metaheuristic algorithms in the active and reactive power management of wind turbines (WTs) integrated into an AC microgrid (MG).
Rubén Iván Bolaños, Héctor Pinto Vega, Luis Fernando Grisales-Noreña, Oscar Danilo Montoya, Jesús C. Hernández   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Mixed-Integer Convex Optimization Framework for Cost-Effective Conductor Selection in Radial Distribution Networks While Considering Load and Renewable Variations

Sci
The optimal selection of conductors (OCS) in radial distribution networks is a critical aspect of system planning, directly impacting both investment costs and energy losses.
Oscar Danilo Montoya, Oscar David Florez-Cediel, Luis Fernando Grisales-Noreña, Walter Gil-González, Diego Armando Giral-Ramírez   +4 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source