Results 111 to 120 of about 124,673 (292)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

On πp--Open Sets in Hereditary Generalized Topological Spaces

open access: yes, 2016
In this paper, we define a new class of set called πp-ℋ-open sets and ( ℋ , λ)-continuous in hereditary generalized topological spaces. Also, we introduce the notions of πp-ℋ-open and πp-ℋ-closed functions by using πp-ℋ-open sets and πp-ℋ-closed sets ...
C Janaki, K Binoy Balan
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

γ*-SEMI-OPEN SETS IN TOPOLOGICAL SPACES

open access: yes, 2010
The concept of generalized open sets in generalized topological spaces was introduced by A. Csaszar [6,7]. In this paper, we introduce the concept of γ*-semi-open sets and investigate the related topological properties of the associated topologies SOγ ...
Sabir Hussain   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Generalized ψρ-Operations on Fuzzy Topological Spaces

open access: yesAbstract and Applied Analysis, 2011
The aim of this work is to introduce ψ-operations on fuzzy topological spaces and to use them to study fuzzy generalized ψρ-closed sets and fuzzy generalized ψρ-open sets.
A. M. Zahran, A. I. El-Maghrabi
doaj   +1 more source

Generalized regular open sets

open access: yesMalaya Journal of Matematik, 2020
Nirani Laxmi   +2 more
openaire   +1 more source

On -Generalized Open and Closed Sets in Neutrosophic Topological Spaces

open access: yes
This article demonstrates a class of neutrosophic closed sets named neutrosophic generalized closed sets, discusses their essential characteristics in neutrosophic topological spaces, and analyses some new interesting theorems based on the newly ...
Rashed, Rukaia M.
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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