Results 111 to 120 of about 17,406,387 (286)
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Generalized energy inequalities and higher multifractal moments [PDF]
, 2014 We present a class of generalized energy inequalities and indicate their use in investigating higher multifractal moments, in particular Lq-dimensions of images of measures under Brownian processes, Lq-dimensions of almost self-affine measures, and moments
Falconer, Kenneth John, Kenneth Falconer
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
On πp--Open Sets in Hereditary Generalized Topological Spaces
, 2016 In this paper, we define a new class of set called πp-ℋ-open sets and ( ℋ , λ)-continuous in hereditary generalized topological spaces. Also, we introduce the notions of πp-ℋ-open and πp-ℋ-closed functions by using πp-ℋ-open sets and πp-ℋ-closed sets ...
C Janaki, K Binoy Balan
core
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Generalized ψρ-Operations on Fuzzy Topological Spaces
Abstract and Applied Analysis, 2011 The aim of this work is to introduce ψ-operations on fuzzy topological spaces and to use them to study fuzzy generalized ψρ-closed sets and fuzzy generalized ψρ-open sets.
A. M. Zahran, A. I. El-Maghrabi
doaj +1 more source