Results 71 to 80 of about 1,262,797 (340)

Generalized Rank Mapped Transmuted Distribution for Generating Families of Continuous Distributions

open access: yesJournal of Statistical Theory and Applications (JSTA), 2021
This study introduces generalized transmuted family of distributions. We investigate the special cases of our generalized transmuted distribution to match with some other generalization available in literature. The transmuted distributions are applied to
M. A. Ali, Haseeb Athar
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Asymptotic behavior of the ground state energy of a Fermionic Fr\"ohlich multipolaron in the strong coupling limit [PDF]

open access: yes, 2016
In this article, we investigate the asymptotic behavior of the ground state energy of the Fr\"ohlich Hamiltonian for a Fermionic multipolaron in the so-called strong coupling limit. We prove that it is given to leading order by the ground state energy of
Anapolitanos, Ioannis, Hott, Michael
core   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Fisher Information, Asymptotic Behavior, and Applications for Generalized Order Statistics and Their Concomitants Based on the Sarmanov Family

open access: yesAxioms, 2023
In this paper, the Fisher information (FI), relevant to m-generalized order statistics (m-GOSs) and their concomitants of the shape-parameter of the Sarmanov family of bivariate distributions, is investigated.
Mohamed A. Abd Elgawad   +6 more
doaj   +1 more source

Generalized decomposition and cross entropy methods for many-objective optimization [PDF]

open access: yes, 2012
Decomposition-based algorithms for multi-objective optimization problems have increased in popularity in the past decade. Although their convergence to the Pareto optimal front (PF) is in several instances superior to that of Pareto-based algorithms ...
Fleming, P.J.   +2 more
core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Some Remarks on Recent Characterizations of Continuous Distributions [PDF]

open access: yes, 2014
We would closely look at two recent published papers dealing with characterizations of certain univariate continuous distributions. We shall explain that the main results reported lack important assumptions.
Hamedani, Gholamhossein
core   +1 more source

Factorial cumulants reveal interactions in counting statistics

open access: yes, 2011
Full counting statistics concerns the stochastic transport of electrons in mesoscopic structures. Recently it has been shown that the charge transport statistics for non-interacting electrons in a two-terminal system is always generalized binomial: it ...
Christian Flindt   +11 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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