Results 71 to 80 of about 2,508,958 (213)

"Empirical Likelihood-Based Inference in Conditional Moment Restriction Models" [PDF]

This paper proposes an asymptotically efficient method for estimating models with conditional moment restrictions. Our estimator generalizes the maximum empirical likelihood estimator (MELE) of Qin and Lawless (1994).
Hyungtaik Ahn, Yuichi Kitamura, Gautam Tripathi   +2 more
core  

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

Tca4rec: contrastive learning with popularity-aware asymmetric augmentation for robust sequential recommendation

Journal of Big Data
Sequential recommender systems play a pivotal role in modern recommendation scenarios by capturing users’ dynamic interests through their historical interactions.
Yanan Bai, Liji Xiao, Chongjun Xia, Kexiang Zeng, Xiaoyu Shi   +4 more
doaj   +1 more source

From Research to Returns: A Firm-Level Analysis of R&D and Productivity in the Human Health Industry

Journal of Technology Management & Innovation
In the rapidly evolving human health industry, the role of research and development (R&D) is pivotal. This study aims to investigate the relationship between R&D and labor productivity in the pharmaceutical, biotechnology, and medical device industries,
Felipe Queiroz Silva, Bernardo Pereira Cabral, Fabio Batista Mota   +2 more
doaj   +1 more source

Import Demand Estimation and the Generalized Composite Commodity Theorem [PDF]

A frequently encountered problem in import demand estimation is how to account for competition between imports and domestic production. Traditionally, use of the Armington model has been a way to handle this problem.
Guttormsen, Atle G., Roheim, Cathy A., Kristofersson, Dadi, Asche, Frank   +3 more
core  

Deep Learning Network‐Tailored Microenvironment Matching of 4D Bioprinting Bioactive Scaffolds for Bone Regeneration

Advanced Science, EarlyView.
A DLN dataset was built to analyze MABS composition versus in vitro/in vivo osteogenesis and angiogenesis. An MLP neural network, taking BG morphological parameters as input, extracts bioactive features from these datasets. A rabbit tibial defect model then validates 4D‐printed MABS for adaptability and bone regeneration in critical defects.
Xiongjie Liang, Yuechi Zhang, Weifeng Hu, Shiyan Lv, Fan Jia, Yan Zhang, Feng Wu, Changjiang Yang, Guanqi Zhen, Jinglong Yan, Xu Cui, Wei Zhao, Guanghua Chen   +12 more
wiley   +1 more source

A Comparative Analysis of the Prediction of Gas Condensate Dew Point Pressure Using Advanced Machine Learning Algorithms

Fuels
Dew point pressure (DPP) emerges as a pivotal factor crucial for forecasting reservoir dynamics regarding condensate-to-gas ratio and addressing production/completion hurdles, alongside calibrating EOS models for integrated simulation.
Thitaree Lertliangchai, Birol Dindoruk, Ligang Lu, Xi Yang, Utkarsh Sinha   +4 more
doaj   +1 more source

GMM with many weak moment conditions [PDF]

Using many moment conditions can improve efficiency but makes the usual GMM inferences inaccurate. Two step GMM is biased. Generalized empirical likelihood (GEL) has smaller bias but the usual standard errors are too small.
Frank Windmeijer, Whitney Newey
core  

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

Generalized Pivotal Quantities And Generalized Confidence Intervals

, 2014
Weerahandi [1] iepazīstina ar vispārinātu pivotālu lielumu un vispārinātu ticamības intervālu konstruēšanas idejām un iegūst atrisinājumus problēmām, kur parastās metodes nedarbojas vai nedod labu rezultātu.
Dāmis, Artis
core