Results 191 to 200 of about 3,187,155 (299)

From Physiology to Bioheat Simulation: A Data‐Driven Framework for Core Temperature Initialization

open access: yesHeat Transfer, EarlyView.
ABSTRACT Accurate initialization of core body temperature is a critical yet often overlooked component of bioheat transfer models, particularly when such models are applied to heterogeneous populations and real‐world environmental conditions. Conventional bioheat simulations typically rely on fixed or idealized core body temperature values derived from
David S. Rodríguez   +6 more
wiley   +1 more source

GSK3β drives early diabetic tubulopathy via TFEB‐mediated mitochondrial dysfunction

open access: yesInterdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction, including mitochondrial biogenesis, mitophagy, dynamics and oxidative stress, occurs in the early stages of diabetic tubulopathy, which precede proteinuria and renal histological changes. GSK3β is a potential novel biomarker for the prediction of diabetic tubulopathy.
Lan Yao   +10 more
wiley   +1 more source

Modular assembly and property profiling of an expansive, shape-defined library of pentacyclic saturated N-heterocycles. [PDF]

open access: yesChem Sci
Boschi E   +12 more
europepmc   +1 more source

Machine Learning‐Based Estimation of Reference Evapotranspiration and Crop Coefficients for Wheat Under Diverse Climatic Conditions

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT Accurate estimation of reference evapotranspiration (ET0) and crop coefficients (Kc) is critical for irrigation planning, particularly in data‐limited regions where agriculture dominates freshwater consumption. Although machine learning (ML) methods have been widely applied to ET0 and Kc estimation, most studies address these parameters ...
Ilker Angin   +4 more
wiley   +1 more source

Deniers and Compliers: Unpacking the Heterogeneous Effectiveness of U.S. Stay‐at‐Home Mandates During the COVID‐19 Pandemic

open access: yesJournal of Applied Econometrics, EarlyView.
ABSTRACT While existing work shows COVID‐19 stay‐at‐home (SAH) policies decreased mobility on average, we lack evidence regarding heterogeneity in policy effectiveness across US counties. To uncover potential heterogeneity, we implement a novel two‐stage approach.
James Sears   +5 more
wiley   +1 more source

A Comprehensive Study to Compare Different Compound Representations for Predicting Carcinogenicity In Vivo

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Carcinogenicity evaluation is a critical component of chemical risk assessment, yet traditional in vivo testing remains time consuming, costly, and ethically challenging. Computational approaches based on machine learning offer promising alternatives, but the relative contributions of different molecular representation strategies for ...
Iuri Barbosa Pereira   +2 more
wiley   +1 more source

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