Results 171 to 180 of about 1,781,268 (316)

A Generalization of the Least General Generalization

A Generalization of the Least General Generalization
In this paper, we describe a polynomial time algorithm, called a k-minimal multiple generalization (k-mmg) algorithm, where $ k gep 1$, and its application to inductive learning problems. The algorithm is a natural extension of the least general generalization algorithm developed by Plotkin.
openaire  

Machine Learning Is Not Just for Prediction: Its Role as an Exploratory Analytical Tool in Medicine. [PDF]

Ann Vasc Dis
Komatsu S.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

ITERATIVE SCHEME GENERATING METHOD FOR CONTRACTION TYPE MAPPINGS IN BANACH SPACES [PDF]

We introduce an iterative scheme generating method (ISGM) for contraction type mappings in Banach spaces. This marks the first time ISGM has been demonstrated in a Banach space setting. Our main theorem can apply to contraction mappings, Kannan mappings,
コンドウ, アツマサ, Kondo, Atsumasa, 近藤, 豊将   +2 more
core  

Ground State Energy Fluctuations of Pinned Elastic Manifolds. [PDF]

J Stat Phys
Fyodorov YV, Lacroix-A-Chez-Toine B, Le Doussal P.   +2 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Agreement between heuristic shrinkage factor and optimal shrinkage factors in logistic regression for risk prediction: a simulation study across different sample sizes and settings. [PDF]

Diagn Progn Res
Pate A, Martin GP, Riley RD.
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Editorial Note: Host-Associated Metagenomics: A Guide to Generating Infectious RNA Viromes. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source