Results 141 to 150 of about 7,049,651 (299)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Generating Random Service Function Chain Embedding Problems
, 2017 The combination of Software Defined Networking (SDN) and Network Function Virtualization (NFV) promises to provide highly flexible and configurable network infrastructures.
Fischer, Andreas,
core
Editors’ introduction: Generating data [PDF]
, 2016 This Major Work collection explores a number of substantive methodologies and focuses on generating data, drawing primarily on literature from sociology, social psychology, social anthropology, and ...
Curtis, Bruce, Curtis, Cate
core
Products of general Fibonomial coefficients via matrices [PDF]
Discrete Mathematics LettersAbdullah Alazemi, Emrah Kılıç
doaj +1 more source
New Properties and Determinantal Representations of Leonardo Finite Operator Polynomials
MathematicsThe aim of this paper is to introduce Leonardo finite operator polynomials and obtain some of their new properties. We first present the recurrence relation provided by Leonardo finite operator polynomials.
Emrah Polatlı +2 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Compiling with Generating Functions
Proceedings of the ACM on Programming LanguagesWe present a new approach to scaling exact inference for probabilistic programs, using generating functions (GFs) as a compilation target. Existing methods that target representations like binary decision diagrams (BDDs) achieve strong state-of-the-art results.
Jianlin Li, Yizhou Zhang 0001
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A New Generating Function of (q-) Bernstein-Type Polynomials and Their Interpolation Function
, 2010 The main object of this paper is to construct a new generating function of the (q-) Bernstein-type polynomials. We establish elementary properties of this function. By using this generating function, we derive recurrence relation and derivative of the (q-
Yilmaz Simsek, Mehmet Acikgoz
core +1 more source