Results 141 to 150 of about 876,906 (306)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Generating function formulation for inverse freeform design [PDF]
We present several geometrical models for freeform optical design based on Hamilton’s characteristic functions, which can be either expressed in terms of a cost function or a generating function. The models are closed with an energy balance.
Braam, P.A. +3 more
core +1 more source
New Properties and Determinantal Representations of Leonardo Finite Operator Polynomials
MathematicsThe aim of this paper is to introduce Leonardo finite operator polynomials and obtain some of their new properties. We first present the recurrence relation provided by Leonardo finite operator polynomials.
Emrah Polatlı +2 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Characteristic function estimation of non-Gaussian Ornstein-Uhlenbeck processes. [PDF]
Continuous non-Gaussian stationary processes of the OU-type are becoming increasingly popular given their flexibility in modelling stylized features of financial series such as asymmetry, heavy tails and jumps.
Emanuele Taufer
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Products of general Fibonomial coefficients via matrices [PDF]
Discrete Mathematics LettersAbdullah Alazemi, Emrah Kılıç
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Probability generating function of GPED 2
Probability generating function, GPED 2 , Order statistics, Range,
A. Bazargan-Lari
core +1 more source
A New Generating Function of (q-) Bernstein-Type Polynomials and Their Interpolation Function
, 2010 The main object of this paper is to construct a new generating function of the (q-) Bernstein-type polynomials. We establish elementary properties of this function. By using this generating function, we derive recurrence relation and derivative of the (q-
Yilmaz Simsek, Mehmet Acikgoz
core +1 more source