Results 221 to 230 of about 2,713,068 (267)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

ALGR: A multi-purpose agricultural landscape generator in R. [PDF]

PLoS One
Goldstein E, Deutscher A, O'Keeffe E, Wiegand K.   +3 more
europepmc   +1 more source

Obtaining Explicit Formulas and Identities for Polynomials Defined by Generating Functions of the Form F(t)^x · G(t)^α

, 2019
Dmitry Kruchinin, Vladimir Kruchinin, Yuriy Shablya   +2 more
openalex   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Evolution and structural diversity of the MotAB stator: insights into the origins of bacterial flagellar motility. [PDF]

mBio
Puente-Lelievre C, Ridone P, Douglas J, Amritkar K, Kaçar B, Baker MAB, Matzke NJ.   +6 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Testosterone Pellets in Women: Revisiting Safety and Clinical Outcomes. [PDF]

Cureus
Pinto da Costa Viana D, Jacobsen L, Gabriel LH, Lobo de Souza Correia E, da Maia Fernandes D, Nagel ML, Comin A.   +6 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Comparing causal inference methods for point exposures with missing confounders: a simulation study. [PDF]

BMC Med Res Methodol
Benz L, Levis AW, Haneuse S.
europepmc   +1 more source

Prediction of ground motion generated by an earthquake : differences of decay between small and large earthquakes and broadband simulations using empirical Green’s functions

, 2015
Alain Dujardin
openalex   +1 more source