Results 261 to 270 of about 764,748 (296)

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

A multilevel Bayesian approach to climate-fueled migration and conflict. [PDF]

open access: yesSci Rep
Palandri C   +4 more
europepmc   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

ALGR: A multi-purpose agricultural landscape generator in R. [PDF]

open access: yesPLoS One
Goldstein E   +3 more
europepmc   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

Testosterone Pellets in Women: Revisiting Safety and Clinical Outcomes. [PDF]

open access: yesCureus
Pinto da Costa Viana D   +6 more
europepmc   +1 more source

The Impact of Hyperbaric Oxygen Therapy in Liver Donors Before Controlled Circulatory Death on Graft Function Recovery: A Pilot Study. [PDF]

open access: yesTranspl Int
Caplan M   +7 more
europepmc   +1 more source

Theoretical aspects and simulation with the application of a new two parameter distribution. [PDF]

open access: yesSci Rep
Ghouar A   +8 more
europepmc   +1 more source

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