Results 261 to 270 of about 876,906 (306)

Statistical and Structural Bias in Birth-Death Models. [PDF]

Bull Math Biol
Beaulieu JM, O'Meara BC.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Illustrating Implications of Misaligned Causal Questions and Statistics in Settings With Competing Events and Interest in Treatment Mechanisms. [PDF]

Stat Med
Kawahara T, McGrath S, Young JG.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

GNTF: A Lightweight CNN Robustness Enhancement Method for IoT Devices. [PDF]

Sensors (Basel)
Liu X, Zhang B, Wang J, Bian H, Ge Y.
europepmc   +1 more source

Correction: Appropriate data segmentation improves speech encoding models: Analysis and simulation of electrophysiological recordings. [PDF]

PLoS One
Bialas O, Lalor EC.
europepmc   +1 more source

A length-biased Sujit distribution framework: properties, simulation-based inference, and application to clinical remission data. [PDF]

Sci Rep
Sindhu TN, Shafiq A, Khatib YE, Abushal TA, Alharthi AS.   +4 more
europepmc   +1 more source

The contribution of mechanical ventilation to critical illness-associated diaphragm dysfunction: a critical appraisal. [PDF]

Crit Care
Rosà T, Doorduin J, Grieco DL, Antonelli M, Ottenheijm CAC, Heunks L.   +5 more
europepmc   +1 more source

Management of Pediatric Mandibular Condyle Fracture and Malocclusion Using a Function-Generating Bite Appliance: A Case Report. [PDF]

Am J Case Rep
Leiva Ramirez EC, Avolese S, Tortarolo A, Vallelonga T, Tonni I, Nucci L, Piancino MG.   +6 more
europepmc   +1 more source