Results 51 to 60 of about 876,906 (306)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Reliability analysis of spherical function generating mechanisms

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
Spherical mechanisms are widely used in engineering applications. Minimizing their motion error is critical for high performance of such mechanisms. The motion error is significantly affected by uncertainties in spherical mechanisms.
Junfu ZHANG
doaj   +1 more source

Cyclotomic Generating Functions

The Electronic Journal of Combinatorics
It is a remarkable fact that for many statistics on finite sets of combinatorial objects, the roots of the corresponding generating function are each either a complex root of unity or zero. These and related polynomials have been studied for many years by a variety of authors from the fields of combinatorics, representation theory, probability, number ...
Sara C. Billey, Joshua P. Swanson
openaire   +2 more sources

On Generalized Stieltjes Functions [PDF]

Constructive Approximation, 2018
It is shown that a function $f$ is a generalized Stieltjes function of order $λ>0$ if and only if $x^{1-λ}(x^{λ-1+k}f(x))^{(k)}$ is completely monotonic for all $k\geq 0$, thereby complementing a result due to Sokal. Furthermore, a characterization of those completely monotonic functions $f$ for which $x^{1-λ}(x^{λ-1+k}f(x))^{(k)}$ is completely ...
Koumandos, Stamatis, Pedersen, Henrik L., Koumandos, Stamatis, Pedersen, Henrik L.   +3 more
openaire   +6 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

A Brief Survey and an Analytic Generalization of the Catalan Numbers and Their Integral Representations

Mathematics, 2023
In the paper, the authors briefly survey several generalizations of the Catalan numbers in combinatorial number theory, analytically generalize the Catalan numbers, establish an integral representation of the analytic generalization of the Catalan ...
Jian Cao, Wen-Hui Li, Da-Wei Niu, Feng Qi, Jiao-Lian Zhao   +4 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Computational and theoretical aspects of iterated generating functions [PDF]

, 2013
The thesis offers an investigation into the analysis of so-called iterated generating functions and the schemes that produce them. Beginning with the study of some ad hoc scheme formulations, the notion of an iterated generating function is introduced ...
Clapperton, James Anthony
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

On modeling pollution-generating technologies [PDF]

Distinguishing between intended ("good") production and unintended or residual ("bad") generation, we introduce the concept of by-production. In by-production technologies, pollution is an output that satises a "costly disposability" assumption and ...
R. Robert Russell, Sushama Murty, Steven B. Levkoff   +2 more
core   +2 more sources