Results 221 to 230 of about 521,431 (264)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

First-passage-based boundary estimation in functional data. [PDF]

PLoS One
Kuzu AT, Celik N.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Paneugenesis: a regenerative systems hypothesis for advancing health promotion. [PDF]

Front Public Health
Becker CM, Hoglund L, Chaney B, Lee JGL, Stellefson M, Davis A.   +5 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Causal Effect Estimation With TMLE: Handling Missing Data and Near Violations of Positivity. [PDF]

Biom J
Wiederkehr C, Heumann C, Schomaker M.
europepmc   +1 more source

Tuning LASSO Models for Propensity Score Weighting and Using Synthetic Negative Control Exposures for Residual Bias Detection. [PDF]

Stat Med
Wyss R, Hansen BB, Hahn G, van der Laan L, Lin KJ.   +4 more
europepmc   +1 more source

Paracrine Factor Local Gradient-Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion-Induced Proliferation. [PDF]

Adv Healthc Mater
Huang YH, Yamashita T, Sudo R.
europepmc   +1 more source

Statistical and Structural Bias in Birth-Death Models. [PDF]

Bull Math Biol
Beaulieu JM, O'Meara BC.
europepmc   +1 more source

Enumeration of multiplex juggling card sequences using generalized q-derivatives

Enumerative Combinatorics and Applications
Yumin Cho, Jaehyun Kim, Jang Soo Kim, Nakyung Lee   +3 more
doaj   +1 more source