Results 251 to 260 of about 2,030,203 (332)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Regulatory bodies must critically assess their role in the wellness wave of supplement marketing. [PDF]

Lancet Reg Health Am
Marcon AR.
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Physics-Informed Neural-Network-Based Generation of Composite Representative Volume Elements with Non-Uniform Distribution and High-Volume Fractions. [PDF]

Polymers (Basel)
Zheng T, Cai C, Yang F, Wang R, Liu W.
europepmc   +1 more source

On (a), we illustrate, for a randomly selected participant, a set of four IMFs, and S₄, generated from the EMD of , and, on (b), we illustrate with the probability density function of the IF of each IMF for the same participant.

Pedro Lencastre (11745362), Rujeena Mathema (21511845), Pedro G. Lind (3544796)   +2 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Pattern avoidance in non-crossing and non-nesting permutations

Enumerative Combinatorics and Applications
Kassie Archer, Robert P. Laudone
doaj   +1 more source

Fluctuation Relations Associated to an Arbitrary Bijection in Path Space. [PDF]

Math Phys Anal Geom
Chétrite R, Marcantoni S.
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Comparing causal inference methods for point exposures with missing confounders: a simulation study. [PDF]

BMC Med Res Methodol
Benz L, Levis AW, Haneuse S.
europepmc   +1 more source