A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Estimating heterogeneous treatment effects for general responses. [PDF]
Gao Z, Hastie T.
europepmc +1 more source
Multivariate generating functions involving Chebyshev polynomials and some of its generalizations involving q-Hermite ones [PDF]
Paweł J. Szabłowski
openalex
A Dirichlet Generating Function for the Coefficients of Euler's Pentagonal Number Theorem [PDF]
Friedjof Tellkamp
openalex +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Pattern avoidance in non-crossing and non-nesting permutations
Kassie Archer, Robert P. Laudone
doaj +1 more source
Bioengineered Humanoid-on-Chip Platforms: Tools for Evaluating the Effects of Environmental Exposure on Human Physiological Barriers. [PDF]
Saglam-Metiner P +5 more
europepmc +1 more source
Sampling in the shift-invariant space generated by the bivariate Gaussian function
José Luis Romero +2 more
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A New Fit Assessment Framework for Common Factor Models Using Generalized Residuals. [PDF]
Sung Y, Han Y, Liu Y.
europepmc +1 more source

