Results 311 to 320 of about 17,207,173 (387)
Mechanism and Therapeutic Progress of One-Carbon Metabolic Key Enzyme: Serine Hydroxymethyltransferase 2 in Cancer. [PDF]
Zhu S+9 more
europepmc +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Artificial intelligence's contribution to biomedical literature search: revolutionizing or complicating? [PDF]
Yip R, Sun YJ, Bassuk AG, Mahajan VB.
europepmc +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki+2 more
wiley +1 more source
Random Walk on T-Fractal with Stochastic Resetting. [PDF]
Sun X, Li A, Zhu S, Zhu F.
europepmc +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Enhanced cell tracking using a GAN-based super-resolution video-to-video time-lapse microscopy generative model. [PDF]
Zargari A, Mashhadi N, Shariati SA.
europepmc +1 more source