Results 81 to 90 of about 1,211,006 (289)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Some New Generating Functions for q-Hahn Polynomials

open access: yesJournal of Applied Mathematics, 2014
We obtain some new generating functions for q-Hahn polynomials and give their proofs based on the homogeneous q-difference operator.
Yun Zhou, Qiu-Ming Luo
doaj   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Minimal passive realizations of generalized Schur functions in Pontryagin spaces [PDF]

open access: yesarXiv, 2019
Passive discrete-time systems in Pontryagin space setting are investigated. In this case the transfer functions of passive systems, or characteristic functions of contractive operator colligations, are generalized Schur functions. The existence of optimal and *-optimal minimal realizations for generalized Schur functions are proved.
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Moments for Generating Functions of Al-Salam-Carlitz Polynomials

open access: yesAbstract and Applied Analysis, 2012
We employ the moment representations for Al-Salam-Carlitz polynomials and show how to deduce bilinear, trilinear, and multilinear generating functions for Al-Salam-Carlitz polynomials. Moreover, we obtain two terminating generating functions for Al-Salam-
Jian Cao
doaj   +1 more source

$p$-Adic multiresolution analyses [PDF]

open access: yesarXiv, 2008
We study $p$-adic multiresolution analyses (MRAs). A complete characterisation of test functions generating a MRA (scaling functions) is given. We prove that only 1-periodic test functions may be taken as orthogonal scaling functions and that all such scaling functions generate Haar MRA.
arxiv  

Generalized Gudermannian function

open access: yesIssues of Analysis, 2018
Wilker and Huygens-type inequalities involving generalized Gudermannian function and its inverse function are established. These results are obtained with the aid of the p-version of the Schwab-Borchardt mean. Generalized one-parameter trigonometric and hyperbolic functions play a crucial role in this paper.
openaire   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

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