Results 81 to 90 of about 493,121 (267)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

SOME BILINEAR GENERATING FUNCTIONS [PDF]

open access: yesProceedings of the National Academy of Sciences, 1969
In the present paper, the author applies some of his earlier results which extend the well-known Hille-Hardy formula for the Laguerre polynomials to certain classes of generalized hypergeometric polynomials in order to derive various generalizations of a bilinear generating function for the Jacobi polynomials proved recently by Carlitz.
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Higher-genus Fay-like identities from meromorphic generating functions

open access: yesSciPost Physics
A possible way of constructing polylogarithms on Riemann surfaces of higher genera facilitates integration kernels, which can be derived from generating functions incorporating the geometry of the surface.
Konstantin Baune, Johannes Broedel, Egor Im, Artyom Lisitsyn, Yannis Moeckli
doaj   +1 more source

A characterization of the Rogers q-hermite polynomials

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1995
In this paper we characterize the Rogers q-Hermite polynomials as the only orthogonal polynomial set which is also 𝒟q-Appell where 𝒟q is the Askey-Wilson finite difference operator.
Waleed A. Al-Salam
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

The Kostant partition functions for twisted Kac-Moody algebras

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2000
Employing the method of generating functions and making use of some infinite product identities like Euler, Jacobi's triple product and pentagon identities we derive recursion relations for Kostant's partition functions for the twisted Kac-Moody ...
Ranabir Chakrabarti   +1 more
doaj   +1 more source

On the sum of partition norms and its connection to norms of partitions with parts greater than one [PDF]

open access: yesNotes on Number Theory and Discrete Mathematics
We study the —the product of the parts of a partition—with emphasis on partitions whose parts all exceed 1. We obtain two bivariate recurrences for the sum of norms over partitions into distinct parts, including a refinement that separates the ...
Meenakshi Rana   +2 more
doaj   +1 more source

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