Results 121 to 130 of about 5,524,457 (299)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2016 From the generation of 1914 to the Millennials, what can generational labels really tell ...
Bristow, J.
core
Investigating a thematic approach to narrative generation
, 2009 Adaptive hypermedia aims to create a tailored experience for users and with narrative generation this dynamic content can be in the form of engaging stories.
Millard, David +2 more
core +1 more source
Next Generation: Kazakhstan, 2024
copyright UK Data Service and data collection copyright owner.The British Council Next Generation research series uncovers the aspirations and needs of young people around the world, focusing on countries that are experiencing significant change. It aims
British Council
core +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A programmable logic controller based laboratory analysis of conventional and intelligent control schemes for non-liner systems [PDF]
, 2015 Published ArticleIntelligent Neural Network (NN) based control schemes have surmounted many of the limitations found in the conventional control approaches such as Proportional Integral Derivative (PID) control.
Van Niekerk, T., Fernandes, J.M.
core
, 2013 Logik är ett gammalt och kraftfullt verktyg för att föra korrekta resonemang och människor har under lång tid studerat och tillämpat olika logiska system. Dessa studier har till stor del fokuserat på logik som innefattar ett binärt sanningsbegrepp, det vill säga logik där en utsaga är antingen sann eller falsk. Givetvis är detta en väldigt begränsad vy
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source