Results 51 to 60 of about 32,346 (266)

Multi-Time-Scale Coordinated Operation of a Combined System with Wind-Solar-Thermal-Hydro Power and Battery Units

Applied Sciences, 2019
The grid connection of intermittent energy sources such as wind power and photovoltaic power generation brings new challenges for the economic and safe operation of renewable power systems.
Dongying Zhang, Ting Du, Hao Yin, Shiwei Xia, Huiting Zhang   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A Multiparadigm Approach for Generation Dispatch Optimization in a Regulated Electricity Market towards Clean Energy Transition

Energies
In Indonesia, the power generation sector is the primary source of carbon emissions, largely due to the heavy reliance on coal-fired power plants, which account for 60% of electricity production.
Suroso Isnandar, Jonathan F. Simorangkir, Kevin M. Banjar-Nahor, Hendry Timotiyas Paradongan, Nanang Hariyanto   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Comprehensive Effects of Operation of Pumped-Storage Hydropower Plants on Downstream Conventional Hydropower Plants [PDF]

长江科学院院报
[Objective] Following the construction of pumped-storage hydropower plant upstream of conventional hydropower plant, its operation alters the original natural inflow process, causing increased frequency of water level fluctuations and intraday flow ...
ZHU De-kang, QIN Rui, CHENG Xiang, GUO Xu-ye
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Generation Units Maintenance in Combined Heat and Power Integrated Systems Using the Mixed Integer Quadratic Programming Approach

Energies, 2020
Yearly generation maintenance scheduling (GMS) of generation units is important in each system such as combined heat and power (CHP)-based systems to decrease sudden failures and premature degradation of units.
Omid Sadeghian, Arash Moradzadeh, Behnam Mohammadi-Ivatloo, Mehdi Abapour, Fausto Pedro Garcia Marquez   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source