Results 51 to 60 of about 47,775 (306)

Cohorts, overlapping generations and consanguinity estimates

Annals of Human Biology, 1983
A number of problems in human population genetics involve determining the effects of non-random mating due to cultural or geographic factors, and therefore requires determination of expectations based on random mating. These expectations are usually taken to be the arithmetic mean of the contributions of all possible pairs drawn from a subpopulation of
openaire   +2 more sources

Concept Forum - The third age: class, cohort or generation? [PDF]

, 2002
In this paper we consider some of the ways that the third age can be thought about and studied. Taking the work of Peter Laslett as our key source, we explore his 'aspirational' approach toward redefining post-working life and look at some of its ...
Gilleard, C, Higgs, P
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

ENTREPRENEURIAL ACUMEN OF ENGINEERING STUDENTS: INPUT IN UNDERSTANDING THE IMPULSE OF BUSINESS START-UPS AMONGST ENGINEER – ENTREPRENEURS IN THE PHILIPPINES

International Journal of Industrial Management, 2017
The research aimed to identify the factors that predict the business intelligence of college students enrolled in engineering programs. Participants involved in study were students that belong to the generational cohort called neo-millennials.
Jaypy T. Tenerife
doaj  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Multi generations in the workforce: Building collaboration

IIMB Management Review, 2012
Organisations the world over in today's rapid growth context are faced with the challenge of understanding a multi-generational workforce and devising policies and processes to build collaboration between them. In its first part, this article synthesises
Vasanthi Srinivasan
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Virtual epilepsy patient cohort: generation and evaluation

PLOS Computational Biology
AbstractEpilepsy is a prevalent brain disorder, characterized by sudden, abnormal brain activity, making it difficult to live with. One-third of people with epilepsy do not respond to anti-epileptic drugs. Drug-resistant epilepsy is treated with brain surgery.
Dollomaja, Borana, Wang, Huifang, Guye, Maxime, Makhalova, Julia, Bartolomei, Fabrice, Jirsa, Viktor   +5 more
openaire   +4 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Changes in the value orientation of the workforce from the perspective of intergenerational disparities in the context of work attitudes and loyalty

Entrepreneurship and Sustainability Issues
The presented study examines labour market changes caused by generational shifts, specifically focusing on employees' value orientation toward work and changes in loyalty.
Richard Rigó, Adriana Grenčíková, Mantas Švažas, Valentinas Navickas   +3 more
doaj   +1 more source