Results 71 to 80 of about 47,775 (306)

Virtual cohort generation and validation

open access: yes, 2023
SIMCor (In-Silico testing and validation of Cardiovascular IMplantable devices) has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 101017578.
openaire   +1 more source

Legal socialization effects on democratization [PDF]

open access: yes, 1997
As is the case with all our joint publications, this article represents a genuine research collaboration between the authors, with equal contributions. Therefore, neither is first or second author. This article uses data from a collaborative project that
Cohn, Ellen S, White, Susan O
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Consolidation of the social capital among different generational cohorts: organizational and subcultural facets

open access: yesСоциальная психология и общество, 2019
The aim of this article is to consider the consolidation of social capital in two Russian state organizations under the context of different generational cohorts, namely, Baby Boomers, Generation X and Y, and the features of their organizational behavior.
Volkova N.V., Chiker V.A., Pochebut L.G.
doaj   +1 more source

Generational policy and the macroeconomic measurement of tax incidence [PDF]

open access: yes
In this paper we show that the generational accounting framework used in macroeconomics to measure tax incidence can, in some cases, yield inaccurate measurements of the tax burden across age cohorts.
Carlos Garriga, Juan Carlos Conesa
core  

What’s sex got to do with it? A family-based investigation of growing up heterosexual during the twentieth century [PDF]

open access: yes, 2008
This paper explores findings from a cross-generational study of the making of heterosexual relationships in East Yorkshire, which has interviewed women and men within extended families.
Brah A.   +25 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The Method for Determining Time-Generation Range

open access: yesSAGE Open, 2020
This article aims to develop a method for identifying generational cohorts based on the quantitative indicators underlying the change in generational phases according to Strauss and Howe.
Oksana S. Karashchuk   +3 more
doaj   +1 more source

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